Medical research

Lung disease and melanoma: A common molecular mechanism?

A Yale-led team of researchers has solved a biological mystery about the common genesis of many serious diseases such as asthma and metastatic melanoma, identifying the first known pathway by which their cellular functions ...

Immunology

Rapid recall to fight familiar foes

The immune system's first encounter with a potential threat is a valuable learning experience. Through a process of genetic recombination, our immune B cells can potentially produce a wide array of B cell receptor (BCR) molecules, ...

Medical research

Central signaling response found in mitochondrial energy diseases

Researchers have identified a master network of signaling molecules that acts like a "fuse box" to regulate the cellular effects of defective energy flow in mitochondrial respiratory chain diseases—a diverse set of difficult-to-treat ...

Oncology & Cancer

Critical pathway in cell cycle may lead to cancer development

A team of scientists at the Salk Institute for Biological Studies has identified why disruption of a vital pathway in cell cycle control leads to the proliferation of cancer cells. Their findings on telomeres, the stretches ...

Genetics

Whole genome or exome sequencing: An individual insight

Focusing on parts rather than the whole, when it comes to genome sequencing, might be extremely useful, finds research in BioMed Central's open access journal Genome Medicine. The research compares several sequencing technologies ...

Immunology

Live and let die: Protein prevents immune cell suicide

A protein called c-FLIP-R is critical to immune cell survival: If this molecule is missing, the cells kill themselves – and are thus no longer able to perform their job fighting off invaders. Now, scientists at the Helmholtz ...

Medical research

Cholesterol sets off chaotic blood vessel growth

A study at the University of California, San Diego School of Medicine identified a protein that is responsible for regulating blood vessel growth by mediating the efficient removal of cholesterol from the cells. Unregulated ...

Diseases, Conditions, Syndromes

Metabolic biomarkers can predict mortality in the ICU

A metabolic profile of intensive care unit (ICU) patients based on biomarkers of four metabolites can be used to accurately predict mortality, according to a new study.

page 7 from 12