Medical research

A Nobel Prize-worthy question: How do we sense heat, cold, touch?

For centuries, understanding the basis for how we detect, process and react to light, sound, temperature, pressure and other environmental signals has been a scientific focus. Science has advanced, and new understanding at ...

Oncology & Cancer

Cell signaling targets in leukemia

Mutations in the enzyme IDH (isocitrate dehydrogenase) are found in 15–20% of acute myeloid leukemia (AML) cases. IDH mutations have been shown to impact cellular differentiation and DNA and histone methylation, but little ...

Medical research

Avian insights into human ciliopathies

Ciliopathies are genetic disorders caused by defects in the structure and function of cilia, microtubule-based organelles present on the surface of almost every cell in the human body, which play crucial roles in cell signaling. ...

Cardiology

New research could reduce the risk of sudden cardiac death

Around 26 million people worldwide suffer from heart failure, with more than 50 per cent dying suddenly most likely due to the spontaneous onset of a heart rhythm problem, known as an arrhythmia. The link between the electrical ...

Medical research

Scientists identify a genetic basis for healthy sleep

From organisms as simple as worms to those as complex as humans, sleep is a fundamental necessity. But although an estimated 50 to 70 million people in the United States suffer from a chronic sleep disorder, the genetic mechanisms ...

Diseases, Conditions, Syndromes

New opportunities for treating kidney failure

Our kidneys can sense when we need them to work a bit harder. As the intestines begin to produce more waste products, the kidneys start to work harder to excrete them. Researchers at, among others, Utrecht University and ...

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