A new study shows that delivery of gene therapy to correct the gene mutations that cause CLN2 disease, or Batten disease, directly into the cerebrospinal fluid (CSF) has potential therapeutic effects. The study, conducted ...
Sep 28, 2023
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Cerebrospinal fluid (CSF) leaks may be one of the mechanisms that link traumatic brain injury (TBI) with dementia, according to a hypothesis in Alzheimer's & Dementia: Translational Research & Clinical Interventions, .
Sep 21, 2023
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New research from Vanderbilt University Medical Center finds that cerebrospinal fluid (CSF) net flow is markedly decreased in Huntington's disease (HD), with the decrease being greater in later stages of the disease.
Sep 13, 2023
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A panel of 48 proteins in the cerebrospinal fluid (CSF 48 panel) complements existing CSF biomarkers for Alzheimer disease (AD), according to a study published in the Sept. 6 issue of Science Translational Medicine.
Sep 8, 2023
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Researchers with the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins University School of Medicine and four other institutions have developed a molecular test to identify the presence of brain tumors by measuring abnormal ...
Sep 6, 2023
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The human body is an intricate network of systems, and central to its operation is the central nervous system (CNS), consisting of the brain and spinal cord—serving as the main command center.
Aug 17, 2023
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For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments. The compound, called ONC201, nearly ...
Aug 16, 2023
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Results of a long-term study of cognitively healthy adults—most with a family history of Alzheimer's disease—have added to evidence that low spinal fluid levels of a protein linked to learning and memory in mice may serve ...
Jul 31, 2023
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Fragile X syndrome is a genetic disorder caused by a mutation in a gene that lies at the tip of the X chromosome. It is linked to autism spectrum disorders. People with fragile X experience a range of symptoms that include ...
Jul 27, 2023
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Alzheimer's is considered a disease of old age, with most people being diagnosed after 65. But the condition actually begins developing, out of sight, many years before any symptoms emerge. Tiny proteins, known as amyloid-beta ...
Jul 20, 2023
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