News tagged with chemical pathway
New test for skin sensitization without using animals
In an advance in efforts to reduce the use of animals in testing new cosmetic and other product ingredients for skin allergies, scientists are describing a new, highly accurate non-animal test for these skin-sensitizers. ...
Medical research
Mar 27, 2013 |
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Some autism behaviors linked to altered gene
Scientists at Washington University School of Medicine in St. Louis have identified a genetic mutation that may underlie common behaviors seen in some people with autism, such as difficulty communicating ...
Neuroscience
Feb 12, 2013 |
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Scientists identify natural compounds that enhance humans' perception of sweetness
(Medical Xpress)—University of Florida taste scientist Linda Bartoshuk and her colleagues want to play a trick on you—but it's for your own good.
Medical research
Jan 16, 2013 |
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New discovery in autism-related disorder reveals key mechanism in brain development and disease
A new finding in neuroscience for the first time points to a developmental mechanism linking the disease-causing mutation in an autism-related disorder, Timothy syndrome, and observed defects in brain wiring, according to ...
Neuroscience
Jan 14, 2013 |
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Scientists identify compounds that could thwart post-traumatic stress disorder
A brain pathway that is stimulated by traumatic or fearful experiences can be disrupted by two compounds that show promise for preventing post-traumatic stress disorder, Indiana University researchers reported.
Psychology & Psychiatry
Oct 15, 2012 |
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Researchers identify promising biomarkers and new therapeutic targets for kidney cancer
Using blood, urine and tissue analysis of a unique mouse model, a team led by UC Davis researchers has identified several proteins as diagnostic biomarkers and potential therapeutic targets for kidney cancer. Subject to follow-up ...
Cancer
May 31, 2012 |
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Genes for learning, remembering, forgetting: Proteins important in embryos found to change the adult brain
Certain genes and proteins that promote growth and development of embryos also play a surprising role in sending chemical signals that help adults learn, remember, forget and perhaps become addicted, University ...
Medical research
Mar 29, 2012 |
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Study shows how the breakup of two proteins interferes with the immune system
Autoimmune diseases, such as Type I diabetes and rheumatoid arthritis, are caused by an immune system gone haywire, where the body's defense system assaults and destroys healthy tissues. A mutant form of a ...
Immunology
Mar 18, 2012 |
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Mitochondrial dysfunction present early in Alzheimer's, before memory loss
Mitochondria -- subunits inside cells that produce energy -- have long been thought to play a role in Alzheimer's disease. Now Mayo Clinic researchers using genetic mouse models have discovered that mitochondria in the brain ...
Alzheimer's disease & dementia
Feb 29, 2012 |
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Modified bone drug kills malaria parasite in mice
A chemically altered osteoporosis drug may be useful in fighting malaria, researchers report in a new study. Unlike similar compounds tested against other parasitic protozoa, the drug readily crosses into ...
Medical research
Feb 27, 2012 |
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Jak of all trades? Not of leukaemia therapy
About one in five or six cases of adult leukaemia in Western populations relates to so-called chronic myeloid leukaemia, or CML. Treatment of CML usually relies on inhibitors of the abnormal protein that causes the condition ...
Cancer
Jan 30, 2012 |
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New discovery could lead to treatment for Angelman syndrome
Results of a new study from the University of North Carolina at Chapel Hill may help pave the way to a treatment for a neurogenetic disorder often misdiagnosed as cerebral palsy or autism.
Genetics
Dec 21, 2011 |
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Tumor-targeting compound points the way to new personalized cancer treatments
One major obstacle in the fight against cancer is that anticancer drugs often affect normal cells in addition to tumor cells, resulting in significant side effects. Yet research into development of less harmful treatments ...
Cancer
Dec 01, 2011 |
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Cell molecule identified as central player in the formation of new blood vessels
Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified a cellular protein that plays a central role in the formation of new blood vessels. The molecule is the protein ...
Medical research
Nov 28, 2011 |
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Tumor-specific pathway identified
A research team led by UT Southwestern Medical Center scientists has identified an atypical metabolic pathway unique to some tumors, possibly providing a future target for drugs that could reduce or halt the spread of cancer.
Cancer
Nov 22, 2011 |
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