News tagged with chemokine
Cancer vaccines that attempt to stimulate an immune system assault fail because the killer T cells aimed at tumors instead find the vaccination site a more inviting target, scientists at The University of Texas MD Anderson ...
Medical research Mar 03, 2013 | 4.8 / 5 (5) | 1 |
(Medical Xpress)—A group of researchers in Austria and Switzerland has for the first time proven that immune cells migrate along chemical concentration gradients. This process has long been assumed but ...
Immunology Jan 18, 2013 | not rated yet | 0 |
Moffitt researchers identify unique immune gene signature across thousands of patients' solid tumors
(Medical Xpress)—Researchers at Moffitt Cancer Center have discovered a unique immune gene signature that can predict the presence of microscopic lymph node-like structures in metastatic melanoma. The presence of these ...
Genetics Oct 25, 2012 | 4.5 / 5 (2) | 0 |
(HealthDay)—A new vaccination approach may provide protection against genital herpes as well as other sexually transmitted infections, including HIV, according to a new study involving mice.
Medical research Oct 17, 2012 | 5 / 5 (5) | 0 |
Diabetic nephropathy is one of the most serious complications related to diabetes, often leading to end-stage kidney disease. Purple corn grown in Peru and Chile is a relative of blue corn, which is readily available in the ...
Medical research Sep 18, 2012 | 4 / 5 (2) | 0
Researchers at NYU School of Medicine have made an important discovery that partially answers the long-standing question of why a mother's immune system does not reject a developing fetus as foreign tissue.
Medical research Jun 07, 2012 | 5 / 5 (7) | 0 |
(Medical Xpress) -- A new technique for improving delivery of stem cells may lead to better and faster tissue repair, a breakthrough with promise for sports medicine and military populations.
Medical research Apr 03, 2012 | 5 / 5 (1) | 0 |
Inflammatory breast cancer (IBC) is the most lethal form of breast cancer . It spreads easily through the lymphatic and blood vessels, forming metastasis which can lead to multi-organ failure. New research published in BioMed ...
Immunology Feb 10, 2012 | not rated yet | 0
Observational epidemiologic studies relating wine and alcohol to health all suffer from the fact that they, of necessity, compare people who prefer certain beverages, but not the beverages themselves. While there have been ...
Cardiology Jan 17, 2012 | not rated yet | 1
New findings about the way cells work could lead to a test and therapy for kidney failure caused by E. coli
Ever since the water supply in Walkerton, Ont., was contaminated by E. coli in 2000, Dr. Philip Marsden has been trying to figure out just how a toxin released by that particular strain of the bacteria causes kidney damage ...
Diseases, Conditions, Syndromes Jan 10, 2012 | not rated yet | 0 |
Researchers at the Medical College of Wisconsin have shown that a protein can inhibit metastasis of colon and melanoma cancers. The findings are published in the October 10, 2011 issue of Proceedings of the National Academy of ...
Cancer Oct 10, 2011 | 5 / 5 (4) | 1 |
Researchers at King's College London have found a molecule in the body which controls sensitivity to pain from UVB irradiation, identifying it as a new target for medicines to treat pain caused by other common ...
Medical research Jul 06, 2011 | not rated yet | 0 |
Researchers from Boston University School of Medicine (BUSM) using a traditional Korean medicine, SO-CHEONG-RYONG-TANG (SCRT) that has long been used for the treatment of allergic diseases in Asia, found that SCRT treatment ...
Diseases, Conditions, Syndromes Jun 30, 2011 | not rated yet | 0
Mast cells, which can help the body respond to bacteria and pathogens, also apparently sound the alarm around viruses delivered by a mosquito bite, according to researchers at Duke-NUS Graduate Medical School in Singapore.
Medical research May 16, 2011 | 2 / 5 (1) | 0 |
Chemokines (Greek -kinos, movement) are a family of small cytokines, or proteins secreted by cells. Their name is derived from their ability to induce directed chemotaxis in nearby responsive cells; they are chemotactic cytokines. Proteins are classified as chemokines according to shared structural characteristics such as small size (they are all approximately 8-10 kilodaltons in size), and the presence of four cysteine residues in conserved locations that are key to forming their 3-dimensional shape. However, these proteins have historically been known under several other names including the SIS family of cytokines, SIG family of cytokines, SCY family of cytokines, Platelet factor-4 superfamily or intercrines. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria, but none have been described for other invertebrates. These proteins exert their biological effects by interacting with G protein-linked transmembrane receptors called chemokine receptors, that are selectively found on the surfaces of their target cells.
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