News tagged with chemotherapeutic agent
A new strategy that takes advantage of ovarian cancer's reliance on folate appears to give relapse patients extra months of life with few side effects, researchers say.
Cancer Oct 28, 2011 | 5 / 5 (1) | 0 |
Scientists may have a way to make the powerful cancer drug cisplatin less toxic to the kidneys and more effective against some cancers.
Cancer Jun 02, 2011 | 4.7 / 5 (3) | 0 |
Brain cancer therapy may be more effective if the expression of an iron-storing protein is decreased to enhance the action of therapeutic drugs on brain cancer cells, according to Penn State College of Medicine researchers.
Cancer Jun 02, 2011 | not rated yet | 0 |
The function of the mitochondria – also defined as "power plants" within the cells – is essential as to whether, and how, some chemotherapeutic agents take effect in tissue. Scientists at the Helmholtz ...
Cancer May 10, 2013 | not rated yet | 0
A study led by Robert G. Hawley, Ph.D., professor and chair of the department of anatomy and regenerative biology at the George Washington University (GW) School of Medicine and Health Sciences (SMHS), may help predict which ...
Cancer Jan 23, 2013 | not rated yet | 0
An Inserm team in Dijon directed by François Ghiringhelli is to publish an article this week in the Nature Medicine review. The article suggests that two chemotherapy drugs frequently used to treat digestive and breast cancers ...
Immunology Dec 04, 2012 | not rated yet | 0
This month, Molecular Pharmaceutics reported promising findings from the Nemours Center for Childhood Cancer Research and the Materials Science and Engineering Department at the University of Delaware, about the potential for na ...
Cancer Dec 04, 2012 | not rated yet | 0
There are plenty of effective anticancer agents around. The problem is that, very often, they cannot gain access to all the cells in solid tumors. A new gene delivery vehicle may provide a way of making tracks to the heart ...
Cancer Nov 14, 2012 | 5 / 5 (1) | 0
Blocking the action of a particular protein in our skin could improve the treatment of skin cancers, according to a study published in Oncogene yesterday by Philippe Roux, a researcher at the University of Montreal's Instit ...
Cancer Oct 31, 2012 | 1 / 5 (1) | 0
Researchers validated a method of noninvasive imaging that provides valuable information about interstitial fluid pressure of solid tumors and may aid in the identification of aggressive tumors, according to the results of ...
Cancer Oct 01, 2012 | not rated yet | 0
Mayo Clinic researchers have found a way to detect and eliminate potentially troublemaking stem cells to make stem cell therapy safer. Induced Pluripotent Stem cells, also known as iPS cells, are bioengineered from adult ...
Medical research Sep 27, 2012 | not rated yet | 0
Patients in early clinical trials of new-style targeted cancer therapies appear to have a much lower risk of the most serious side-effects than with traditional chemotherapy, according to a new analysis.
Cancer Aug 07, 2012 | not rated yet | 0
(Medical Xpress) -- Expression levels of a DNA repair gene called MGMT have been widely studied across many cancers as a biomarker of response to temozolomide, a chemotherapeutic agent. Now Australian scientists have published ...
Cancer Jul 30, 2012 | not rated yet | 0
ATRA and arsenic trioxide versus ATRA and idarubicin for newly diagnosed, non high-risk acute promyelocytic
New research demonstrates the efficacy of the first curative treatment for acute promyelocytic leukemia (APL) that does not include chemotherapy, marking an important step toward front-line use of targeted therapies for acute ...
Cancer Dec 09, 2012 | not rated yet | 0
Few available treatment options exist once prostate cancer has spread to other parts of the body and has failed to respond to therapies that involve blocking the male hormone androgen. Patients with advanced, hormone-refractory ...
Cancer Nov 07, 2012 | not rated yet | 0
Chemotherapy, in its most general sense, refers to treatment of disease by chemicals that kill cells, both good and bad, but specifically those of micro-organisms or cancerous tumours. In popular usage, it refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a cytotoxic standardized treatment regimen. In its non-oncological use, the term may also refer to antibiotics (antibacterial chemotherapy). In that sense, the first modern chemotherapeutic agent was Paul Ehrlich's arsphenamine, an arsenic compound discovered in 1909 and used to treat syphilis. This was later followed by sulfonamides discovered by Domagk and penicillin discovered by Alexander Fleming.
Most commonly, chemotherapy acts by killing cells that divide rapidly, one of the main properties of cancer cells. This means that it also harms cells that divide rapidly under normal circumstances: cells in the bone marrow, digestive tract and hair follicles; this results in the most common side effects of chemotherapy—myelosuppression (decreased production of blood cells), mucositis (inflammation of the lining of the digestive tract) and alopecia (hair loss).
Other uses of cytostatic chemotherapy agents (including the ones mentioned below) are the treatment of autoimmune diseases such as multiple sclerosis and rheumatoid arthritis and the suppression of transplant rejections (see immunosuppression and DMARDs). Newer anticancer drugs act directly against abnormal proteins in cancer cells; this is termed targeted therapy.
For more information about Chemotherapy, read the full article at
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