Study IDs key protein for cell death, offers way to kill cancer cells by forcing them into programmed-death pathway
When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ...
Genetics
May 14, 2013 |
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Research predicts how cancers will respond to chemo, rewrites old theory of why chemo works
Challenging a half-century-old theory about why chemotherapy agents target cancer, scientists at Dana-Farber Cancer Institute have devised a test that can predict how effective the drugs will be by determining whether a patient's ...
Cancer
Oct 27, 2011 |
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Gene therapy reduces HIV levels in small trials
(Medical Xpress) -- This weekend at the Interscience Conference on Antimicrobial Agents and Chemotherapy in Chicago, Illinois, researchers from two different study groups, one on the east coast and one on the west coast, ...
HIV & AIDS
Sep 20, 2011 |
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Breast cancer drug pushes colon cancer cells to their death
A new treatment for colon cancer that combines a chemotherapy agent approved to treat breast cancer and a cancer-fighting antibody is ready for clinical trials, according to Penn State College of Medicine researchers.
Cancer
Jun 08, 2011 |
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Molecule's role in cancer suggests new combination therapy
Researchers at the University of Illinois at Chicago College of Medicine have found that a molecule found at elevated levels in cancer cells seems to protect them from the "cell-suicide" that is usually triggered by chemotherapy ...
Cancer
Mar 01, 2012 |
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New drug strategy attacks resistant leukemia and lymphoma
Scientists at the Dana-Farber/Children's Hospital Cancer Center have developed an anti-cancer peptide that overcomes the stubborn resistance to chemotherapy and radiation often encountered in certain blood cancers when the ...
Cancer
May 29, 2012 |
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'Repurposed' anti-parasite drug shows promise as new TB treatment
(Medical Xpress)—A well-established family of drugs used to treat parasitic diseases is showing surprising potential as a therapy for tuberculosis (TB), according to new research from University of British Columbia microbiologists.
Diseases, Conditions, Syndromes
Nov 23, 2012 |
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Newly discovered reservoir of antibiotic resistance genes
Waters polluted by the ordure of pigs, poultry, or cattle represent a reservoir of antibiotic resistance genes, both known and potentially novel. These resistance genes can be spread among different bacterial species by bacteriophage, ...
Medical research
Oct 21, 2011 |
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Scientists reprogram cancer cells with low doses of epigenetic drugs
Experimenting with cells in culture, researchers at the Johns Hopkins Kimmel Cancer Center have breathed possible new life into two drugs once considered too toxic for human cancer treatment. The drugs, azacitidine (AZA) ...
Cancer
Mar 22, 2012 |
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Research finds novel airborne germ-killing oral spray effective in fighting colds and flu
University Hospitals Case Medical Center clinical researchers will present findings about a one-two punch to prevent colds and flu in San Francisco at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) ...
Diseases, Conditions, Syndromes
Sep 09, 2012 |
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Stem cell study: Male fertility can be restored after cancer treatment
An injection of banked sperm-producing stem cells can restore fertility to male primates who become sterile due to cancer drug side effects, according to researchers at the University of Pittsburgh School of Medicine and ...
Medical research
Nov 01, 2012 |
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Researchers identify gene variations that predict chemotherapy side effects
Seemingly benign differences in genetic code from one person to the next could influence who develops side effects to chemotherapy, a Mayo Clinic study has found. The study identified gene variations that can predispose people ...
Cancer
Apr 09, 2013 |
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Discovery holds potential in destroying drug-resistant bacteria
Through the serendipity of science, researchers at the University of Pittsburgh have discovered a potential treatment for deadly, drug-resistant bacterial infections that uses the same approach that HIV uses to infect cells. ...
Medical research
May 07, 2013 |
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Old is new again: Study determines dosing for 1950s drug now being used to treat drug-resistant infections
(Medical Xpress) -- An ongoing study led by a University of Pittsburgh researcher has established the first scientifically-based dosing guidelines for a more than 50-year-old drug that has re-emerged as the best, and often ...
Medications
Jul 04, 2011 |
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