News tagged with chemotherapy

Research identifies a way to make cancer cells more responsive to chemotherapy

Breast cancer characterized as "triple negative" carries a poor prognosis, with limited treatment options. In some cases, chemotherapy doesn't kill the cancer cells the way it's supposed to. New research from Western University ...

Cancer created May 23, 2013 | popularity 5 / 5 (3) | comments 0

Improved chemo regimen for childhood leukemia may offer high survival, no added heart toxicity

Treating pediatric leukemia patients with a liposomal formulation of anthracycline-based chemotherapy at a more intense-than-standard dose during initial treatment may result in high survival rates without causing any added ...

Cancer created May 23, 2013 | popularity not rated yet | comments 0

Beta-blockers may boost chemo effect in childhood cancer

Beta-blockers, normally used for high blood pressure, could enhance the effectiveness of chemotherapies in treating neuroblastoma, a type of children's cancer, according to a new study published in the British Jo ...

Cancer created May 22, 2013 | popularity not rated yet | comments 0

Commonly used catheters double risk of blood clots in ICU and cancer patients

Touted for safety, ease and patient convenience, peripherally inserted central catheters have become many clinicians' go-to for IV delivery of antibiotics, nutrition, chemotherapy, and other medications.

Diseases, Conditions, Syndromes created May 20, 2013 | popularity not rated yet | comments 0

Awakening to new drugs against sleeping sickness

Sleeping sickness kills tens of thousands of people in Africa each year. Current chemotherapies are subject to various limitations, including resistance. Rhodesain, an enzyme of the parasites that cause this ...

Cancer created May 17, 2013 | popularity 4 / 5 (1) | comments 1 | with audio podcast

Research to end asbestos-related cancer

Scientists from Flinders University are trying to develop a new treatment for a highly aggressive, asbestos-related lung cancer that is set to become more prevalent in the future.

Cancer created May 16, 2013 | popularity 5 / 5 (1) | comments 0

Preclinical tests shows agent stops 'slippery' proteins from binding, causing Ewing sarcoma

Continuous infusion of a novel agent not only halted the progression of Ewing sarcoma in rats, while some tumors also regressed to the point that cancer cells could not be detected microscopically, say researchers at Georgetown ...

Cancer created May 15, 2013 | popularity not rated yet | comments 0

FDA approves genetic test for lung cancer drug

The Food and Drug Administration says it approved a genetic test from Roche to help doctors identify patients who can benefit from a lung cancer drug made by Genentech.

Medications created May 14, 2013 | popularity not rated yet | comments 0

Study IDs key protein for cell death, offers way to kill cancer cells by forcing them into programmed-death pathway

When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ...

Genetics created May 14, 2013 | popularity 5 / 5 (9) | comments 0 | with audio podcast

Women have more options for breast cancer surgery (Update 2)

One of the world's most glamorous women had an operation that once was terribly disfiguring—removal of both breasts. But new approaches are dramatically changing breast surgeries, whether to treat cancer or to prevent it ...

Cancer created May 14, 2013 | popularity not rated yet | comments 0

Individual efficacy of chemotherapies

The function of the mitochondria – also defined as "power plants" within the cells – is essential as to whether, and how, some chemotherapeutic agents take effect in tissue. Scientists at the Helmholtz ...

Cancer created May 10, 2013 | popularity not rated yet | comments 0

Discovery holds potential in destroying drug-resistant bacteria

Through the serendipity of science, researchers at the University of Pittsburgh have discovered a potential treatment for deadly, drug-resistant bacterial infections that uses the same approach that HIV uses to infect cells. ...

Medical research created May 07, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Initiation of breast cancer treatment varies by race; patient-doctor communication is key

Black women with breast cancer were found to be three times more likely than their white counterparts to delay treatment for more than 90 days—a time delay associated with increased deaths from the disease, according to ...

Cancer created May 07, 2013 | popularity not rated yet | comments 0

Exercise could reduce bone tumor growth

(Medical Xpress)—Weight-bearing exercise, often prescribed to combat bone loss, might have anti-cancer effects. Cornell biomedical researchers report that mechanical stimulation of cancerous bone, in making ...

Cancer created May 07, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Discovery may help prevent chemotherapy-induced anemia

Cancer chemotherapy can cause peripheral neuropathy—nerve damage often resulting in pain and muscle weakness in the arms and legs. Now, researchers at Albert Einstein College of Medicine of Yeshiva University have discovered ...

Medical research created May 05, 2013 | popularity 3 / 5 (1) | comments 0 | with audio podcast

Chemotherapy

Chemotherapy, in its most general sense, refers to treatment of disease by chemicals that kill cells, both good and bad, but specifically those of micro-organisms or cancerous tumours. In popular usage, it refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a cytotoxic standardized treatment regimen. In its non-oncological use, the term may also refer to antibiotics (antibacterial chemotherapy). In that sense, the first modern chemotherapeutic agent was Paul Ehrlich's arsphenamine, an arsenic compound discovered in 1909 and used to treat syphilis. This was later followed by sulfonamides discovered by Domagk and penicillin discovered by Alexander Fleming.

Most commonly, chemotherapy acts by killing cells that divide rapidly, one of the main properties of cancer cells. This means that it also harms cells that divide rapidly under normal circumstances: cells in the bone marrow, digestive tract and hair follicles; this results in the most common side effects of chemotherapy—myelosuppression (decreased production of blood cells), mucositis (inflammation of the lining of the digestive tract) and alopecia (hair loss).

Other uses of cytostatic chemotherapy agents (including the ones mentioned below) are the treatment of autoimmune diseases such as multiple sclerosis and rheumatoid arthritis and the suppression of transplant rejections (see immunosuppression and DMARDs). Newer anticancer drugs act directly against abnormal proteins in cancer cells; this is termed targeted therapy.

For more information about Chemotherapy, read the full article at Wikipedia.
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