Scientists at Northwestern Medicine have developed a novel therapy to trick cancer cells into gobbling up what they think is their favorite food—cholesterol—which actually triggers their destruction. What appears to them ...
Jan 26, 2021
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963
The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol—the so-called "bad" cholesterol—by 50 percent in patients with severe hypercholesterolemia whose condition is resistant to standard ...
Nov 15, 2020
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78
An injectable drug used to reduce stubbornly high cholesterol levels appears in animal studies to also enhance the immune response of anti-cancer therapies known as immune checkpoint inhibitors, a study led by Duke Health ...
Nov 12, 2020
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143
An experimental antibody drug that targets one of the body's key metabolism regulators may help obese people lose weight—at least briefly.
Nov 3, 2020
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38
Precision medicine has the potential to tailor treatments to a patient's unique genetic sequence. But achieving this precision—or developing new drugs—requires knowing which genes are involved in disease.
May 4, 2020
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142
The cholesterol drug alirocumab reduced low-density lipoprotein (LDL) cholesterol by 35.6% compared to placebo in adult patients with homozygous familial hypercholesterolemia (HoFH), according to a phase three clinical trial ...
Mar 30, 2020
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0
A drug used to treat and prevent HIV/AIDS is showing promise as a potential therapy for Alzheimer's disease, and Vanderbilt University biochemist F. Peter Guengerich, Ph.D., is aiding efforts to make this approach to improving ...
Dec 16, 2019
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250
A new drug developed at Yale reduces a host of abnormalities associated with metabolic syndrome, an obesity-born condition that afflicts one of three adults in the United States, researchers report Oct. 2 in the journal Science ...
Oct 3, 2019
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235
Hypercholesterolemia is a major risk factor for cardiovascular disease. Statins are the most widely used cholesterol-lowering drugs. However, despite treatment with statins, many patients with elevated cholesterol levels ...
Jun 14, 2019
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1
Soy protein has the ability to lower cholesterol by a small but significant amount, suggests a new study led by St. Michael's Hospital in Toronto.
May 6, 2019
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