Researchers from the Mitochondrial Medicine Frontier Program at Children's Hospital of Philadelphia (CHOP) have developed a comprehensive sequencing test specifically for mitochondrial DNA (mtDNA). This new clinical diagnostic ...
Jan 25, 2022
0
29
The urea cycle is responsible for removing nitrogenous waste produced from the breakdown of protein in the organism. If the OTC enzyme is missing in this cycle, ammonia accumulation rises to toxic levels. An OTC deficiency ...
Jan 17, 2022
0
11
Hereditary diseases as well as cancers and cardiovascular diseases may be associated with a phenomenon known as genomic imprinting, in which only the maternally or paternally inherited gene is active. An international research ...
Jan 12, 2022
0
33
In Down syndrome, the third copy of chromosome 21 causes a reorganization of the 3D configuration of the entire genome in a key cell type of the developing brain, a new study shows. The resulting disruption of gene transcription ...
Jan 6, 2022
0
134
An international team of researchers has now comprehensively profiled and categorized over 700 tumor samples from patients with chronic lymphocytic leukemia (CLL) by analyzing multiple levels of encoded biologic information.
Dec 6, 2021
0
5
Consider 100 baby boys and 100 baby girls born in 1950. Experts predict that 46 of the men and 61 of the women—a third more—will still be alive at age 80 in 2030.
Nov 22, 2021
0
12
As widely-anticipated decisions about COVID-19 vaccine boosters roll out from U.S. agencies today, insights from an independent study underscore why boosters are important for all adults.
Nov 19, 2021
0
10
Japanese researchers identified chromosome aberrations as a new biomarker in predicting an esophageal cancer patient's risk of experiencing severe chemoradiotherapy side effects.
Oct 29, 2021
0
34
Writing in EMBO reports, researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health describe how a pair of fundamental genetic and cellular processes are exploited ...
Oct 26, 2021
0
32
Past neuroscience research suggests that common differences in people's genetic profiles can explain a significant proportion of variations in people's brain anatomy. In more specific terms, they found that neuroanatomical ...
