News tagged with clinical model

Itching for new help for eczema: Recently identified immune cells possible therapeutic target

Researchers have identified a previously unknown critical role for a recently identified immune cell population in the progression of atopic dermatitis. The team found an accumulation of innate lymphoid cells ...

Immunology Jan 30, 2013 | 5 / 5 (1) | 0 |

Study identifies biological mechanism that plays key role in early-onset dementia

Using animal models, scientists at the Gladstone Institutes have discovered how a protein deficiency may be linked to frontotemporal dementia (FTD)—a form of early-onset dementia that is similar to Alzheimer's disease. ...

Neuroscience Oct 08, 2012 | not rated yet | 0 |

Experimental drug could help reduce brain damage, improve motor skills after stroke

(Medical Xpress)—A University of Arizona professor is overseeing the manufacture of an experimental drug that could help reduce brain damage after a stroke.

Medical research Sep 21, 2012 | 5 / 5 (1) | 1 |

Mathematical model helps design efficient multi-drug therapies

For years, doctors treating those with HIV have recognized a relationship between how faithfully patients take the drugs they prescribe, and how likely the virus is to develop drug resistance. More recently, research has ...

Medical research Sep 02, 2012 | not rated yet | 0 |

'Very promising' treatment for Huntington disease discovered

Medical researchers at the University of Alberta have discovered a promising new therapy for Huntington disease that restores lost motor skills and may delay or stop the progression of the disease based on lab model tests, ...

Diseases, Conditions, Syndromes Feb 13, 2012 | 5 / 5 (9) | 1 |

Differences between 'marathon mice' and 'couch potato mice' reveal key to muscle fitness

Researchers discovered that small pieces of genetic material called microRNAs link the two defining characteristics of fit muscles: the ability to burn sugar and fat and the ability to switch between slow- ...

Medical research May 08, 2013 | 5 / 5 (2) | 0 |

Transcription factors regulating blood oxygen linked to melanoma metastases

Researchers at the University of North Carolina have discovered that transcription factors regulating the levels of oxygen in the blood also play a role in the spread of the skin cancer melanoma.

Cancer Apr 16, 2013 | not rated yet | 0 |

Researchers create next-generation Alzheimer's disease model

A new genetically engineered lab rat that has the full array of brain changes associated with Alzheimer's disease supports the idea that increases in a molecule called beta-amyloid in the brain causes the ...

Alzheimer's disease & dementia Apr 09, 2013 | 5 / 5 (3) | 0 |

Feeling hungry may protect the brain against Alzheimer's disease, study finds

The feeling of hunger itself may protect against Alzheimer's disease, according to study published today in the journal PLOS ONE. Interestingly, the results of this study in mice suggest that mild hunger ...

Alzheimer's disease & dementia Apr 03, 2013 | 5 / 5 (6) | 1 |

New strategy prevents rheumatoid arthritis in mice

Dana-Farber Cancer Institute scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis in a mouse model. They say it holds promise for improved ...

Arthritis & Rheumatism Feb 08, 2013 | 5 / 5 (3) | 0 |

New study sheds light on the complexity of gene therapy for congenital blindness

Independent clinical trials, including one conducted at the Scheie Eye Institute at the Perelman School of Medicine, have reported safety and efficacy for Leber congenital amaurosis (LCA), a congenital form of blindness caused ...

Genetics Jan 22, 2013 | 5 / 5 (3) | 0 |

Two-drug combination may slow deadly thyroid cancer

A combination of the drugs pazopanib and paclitaxel shows promise in slowing anaplastic thyroid cancer (ATC), according to a Mayo Clinic-led study published in the journal Science Translational Medicine. The two drugs togeth ...

Cancer Jan 08, 2013 | 5 / 5 (1) | 0 |

When will genomic research translate into clinical care—and at what cost?

Genomic research is widely expected to transform medicine, but progress has been slower than expected. While critics argue that the genomics "promise" has been broken – and that money might be better spent elsewhere—proponents ...

Genetics Jan 04, 2013 | not rated yet | 0 |

Team finds molecule that polices TB lung infection, could lead to vaccine

The presence of a certain molecule allows the immune system to effectively police tuberculosis (TB) of the lungs and prevent it from turning into an active and deadly infection, according to a new study led by researchers ...

Diseases, Conditions, Syndromes Jan 02, 2013 | not rated yet | 0 |

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