News tagged with clinical oncology


Scientists identify genetic signatures for aggressive form of prostate cancer

Scientists have discovered two separate genetic 'signatures' for prostate cancer that appear to be able to predict the severity of the disease, leading to hopes that in future, accuracy of prognosis and treatment of the disease ...

Cancer created Oct 08, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New drug may help immune system fight cancer

(HealthDay)—An experimental drug that taps the power of the body's immune system to fight cancer is shrinking tumors in patients for whom other treatments have failed, an early study shows.

Cancer created May 16, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

New brain cancer treatment may be more effective, less toxic

(Medical Xpress)—A Phase 2 clinical trial testing a new protocol for treating a relatively rare form of brain cancer, primary CNS lymphoma, may change the standard of care for this disease, according to ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0 | with audio podcast

New research challenges notion of using Herceptin only for HER2-positive breast cancer

New research from the University of Michigan Comprehensive Cancer Center finds that the protein HER2 plays a role even in breast cancers that would traditionally be categorized as HER2-negative – and that ...

Cancer created Feb 26, 2013 | popularity not rated yet | comments 0 | with audio podcast

Study drug is first to help patients with recurrent low-grade ovarian cancer

Low-grade serous ovarian cancer is less common and aggressive than the high-grade variety, yet exceptionally difficult to treat when frontline therapy fails.

Cancer created Feb 08, 2013 | popularity not rated yet | comments 0 | with audio podcast

Spin and bias in published studies of breast cancer trials

Spin and bias exist in a high proportion of published studies of the outcomes and adverse side-effects of phase III clinical trials of breast cancer treatments, according to new research published in the cancer journal Annals of ...

Cancer created Jan 09, 2013 | popularity not rated yet | comments 0 | with audio podcast

Researchers discover new pathways that drive metastatic prostate cancer

Elevated levels of Cyclin D1b could function as a novel biomarker of lethal metastatic disease in prostate cancer patients, according to a pre-clinical study published ahead of print on December 21 in the Journal of Clinical In ...

Cancer created Dec 21, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Older and younger chronic leukemia patients may need different therapy

Doctors should use different therapies when treating older and younger patients with chronic lymphocytic leukemia, according to a new study led by researchers at the Ohio State University Comprehensive Cancer Center – Arthur ...

Cancer created Dec 12, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers report first success of targeted therapy in most common non-small cell lung cancer

A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone ...

Cancer created Nov 28, 2012 | popularity not rated yet | comments 0 | with audio podcast

Delaying treatment for advanced breast cancer more than 60 days has 'profound effect', researchers find

(Medical Xpress)—Results from a new study conducted by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James) show ...

Cancer created Nov 22, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Pathway identified in human lymphoma points way to new blood cancer treatments

A pathway called the "Unfolded Protein Response," or UPR, a cell's way of responding to unfolded and misfolded proteins, helps tumor cells escape programmed cell death during the development of lymphoma.

Cancer created Nov 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Ovarian cancer patients have lower mortality rates when treated at high-volume hospitals

A study by researchers at the Herbert Irving Comprehensive Cancer Center (HICCC) at NewYork-Presbyterian/Columbia University Medical Center, recently e-published ahead of print by the Journal of Clinical Oncology, sugges ...

Cancer created Nov 08, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Older breast cancer patients see more complications with brachytherapy

heralded for its low complication rates—actually results in more complications than whole-breast radiation one year after treatment, Yale School of Medicine researchers report in the October issue of the Journal of Clinical On ...

Cancer created Oct 22, 2012 | popularity not rated yet | comments 0 | with audio podcast

Review finds some evidence for 'chemo brain' in breast cancer survivors

(Medical Xpress)—A large meta-analysis conducted by researchers at Moffitt Cancer Center has concluded that breast cancer patients treated with chemotherapy are at risk for mild cognitive deficits after treatment. The meta-analysis, ...

Cancer created Sep 04, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study pinpoints malignant mesothelioma patients likely to benefit from drug pemetrexed

Previous studies have hypothesized that low levels of the enzyme thymidylate synthase (TS) likely mark patients who will benefit from the drug pemetrexed – but results have been inconclusive at best and at times contradictory. ...

Cancer created Aug 29, 2012 | popularity not rated yet | comments 0 | with audio podcast