News tagged with clinical response

Hijacking stress response in cancer

(Medical Xpress)—Cancer cells have alteration in metabolic pathways as a result of oncogenes that promote tumor growth. NRF2 (nuclear factor erythroid-derived 2-related factor 2) works as a "master gene" that turns on stress ...

Jul 02, 2013
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Modified immune cells seek and destroy melanoma

In this issue of the Journal of Clinical Investigation, researchers led by Scott Pruitt at Duke University and Merck Research Laboratories report on a human clinical trial in which modified dendritic cells, a component of the ...

Jun 24, 2013
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Individual efficacy of chemotherapies

The function of the mitochondria – also defined as "power plants" within the cells – is essential as to whether, and how, some chemotherapeutic agents take effect in tissue. Scientists at the Helmholtz ...

May 10, 2013
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