News tagged with clinical response

Cancer immunotherapy on the cusp

Glass crystals with thread-like filaments floating inside sit in the offices of two prominent immunologists. The clear blocks encase models of the structure of PD-1/PD-L1, a receptor-ligand pair that rides ...

Sep 08, 2014
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Balancing T cell populations

Depending on the signals received, naïve T cells are able to differentiate into mature T cell populations, which play different roles in the immune system. For example, regulatory T cells (Tregs) are important for tamping ...

Nov 25, 2013
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Itch maintains regulatory T cell stability

Regulatory T cells (Tregs) function to suppress immune responses of other cells, and their dysfunction has been associated with development of immune disorders. Recent studies suggest that Tregs maintain plasticity even after ...

Oct 26, 2013
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