Oncology & Cancer

Injected bacteria shrink tumors in rats, dogs and humans

A modified version of the Clostridium novyi (C. noyvi-NT) bacterium can produce a strong and precisely targeted anti-tumor response in rats, dogs and now humans, according to a new report from Johns Hopkins Kimmel Cancer ...

Medical research

Compounds kill C. diff, don't affect other gut bacteria in vitro

NC State researchers developed a drug-testing pipeline to help identify compounds that worked against the three stages of Clostridium difficile infection, and found that a compound that holds promise for treating antibiotic-resistant ...

Diseases, Conditions, Syndromes

A major step forward in fighting superbugs

New research has identified a novel mechanism by which humans can defend themselves against the well known hospital superbug, Clostridium difficile.  The study provides us with critical information for the development ...

Diseases, Conditions, Syndromes

Researchers discover potential antidote to botulism

Researchers have identified a compound that strongly inhibits botulinum neurotoxin, the most toxic compound known. That inhibiting compound, nitrophenyl psoralen (NPP), could be used as a treatment to reduce paralysis induced ...

Diseases, Conditions, Syndromes

Collagenase clostridium histolyticum OK in Peyronie's

(HealthDay)—For patients with Peyronie's disease, treatment with collagenase clostridium histolyticum (CCH) intralesional injections is efficacious and tolerable, according to research published online Feb. 1 in The Journal ...

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Clostridium

Clostridium is a genus of Gram-positive bacteria, belonging to the Firmicutes. They are obligate anaerobes capable of producing endospores. Individual cells are rod-shaped, which gives them their name, from the Greek kloster (κλωστήρ) or spindle. These characteristics traditionally defined the genus, however many species originally classified as Clostridium have been reclassified in other genera.

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