The number of overdose deaths involving methamphetamines and amphetamines in the state of Ohio increased more than 5,000 percent over the course of eight years, according to data collected by the Ohio Alliance for Innovation ...
Oct 26, 2018
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A team with members affiliated with several institutions in the U.S. has found that disabling the gene responsible for the production of the protein tyrosine phosphatase D (PTPRD) caused test mice to self-administer less ...
There are no approved medications to treat either cocaine addiction or overdose. Frequent users tend to become less and less sensitive to the drug, leading to stronger or more frequent doses. The typical result is addiction. ...
Sep 17, 2018
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A study in cocaine-addicted rats reports long-lasting increases in the number of neurons that produce orexin—a chemical messenger important for sleep and appetite—that may be at the root of the addiction. The study, performed ...
Sep 12, 2018
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A class of proteins that has generated significant interest for its potential to treat diseases, has for the first time, been shown to be effective in reducing relapse, or drug-seeking behaviors, in a preclinical study.
Aug 14, 2018
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Exercise can help prevent relapses into cocaine addiction, according to new research led by the University at Buffalo's Panayotis (Peter) Thanos, Ph.D.
Aug 8, 2018
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Cocaine relapse was significantly reduced in a preclinical model when brain-derived neurotropic factor (BDNF) was applied to the nucleus accumbens deep in the brain immediately before cocaine-seeking behavior, report investigators ...
Aug 3, 2018
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Bile acids that aid fat digestion are also found to reduce the rewarding properties of cocaine use, according to a study publishing on July 26 in the open-access journal PLOS Biology by India Reddy, Nicholas Smith, and Robb ...
Jul 26, 2018
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Childhood adversity permanently alters the peripheral and central immune systems, increasing the sensitivity of the body's immune response to cocaine, reports a study by researchers at the IRCCS Santa Lucia Foundation and ...
Jul 17, 2018
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Cocaine can have a devastating effect on people. It directly stimulates the brain's reward center, and, more importantly, induces long-term changes to the reward circuitry that are responsible for addictive behaviors. Alban ...
Jul 12, 2018
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