News tagged with cocaine

Related topics: brain , drug , neurons

Antibody builders

Antibodies are often the first line of defense against the body's invaders.  Built to recognize and attack foreign bacteria and viruses, antibody molecules are released by cells to do battle with microbial ...

Nov 19, 2013
popularity 5 / 5 (3) | comments 1

Study examines nicotine as a gateway drug

A landmark study in mice identifies a biological mechanism that could help explain how tobacco products could act as gateway drugs, increasing a person's future likelihood of abusing cocaine and perhaps other drugs as well, ...

Nov 02, 2011
popularity 3.3 / 5 (3) | comments 0 | with audio podcast

Cocaine

Cocaine (benzoylmethylecgonine) is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" in addition to the alkaloid suffix -ine, forming cocaine. It is both a stimulant of the central nervous system and an appetite suppressant. Specifically, it is a dopamine reuptake inhibitor, a norepinephrine reuptake inhibitor and a serotonin reuptake inhibitor, which mediates functionality of such as an exogenous DAT ligand. Because of the way it affects the mesolimbic reward pathway, cocaine is addictive.

Its possession, cultivation, and distribution are illegal for non-medicinal and non-government sanctioned purposes in virtually all parts of the world. Although its free commercialization is illegal and has been severely penalized in virtually all countries, its use worldwide remains widespread in many social, cultural, and personal settings.

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