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Resetting addicted brain: Laser light zaps away cocaine addiction

By stimulating one part of the brain with laser light, researchers at the National Institutes of Health (NIH) and the Ernest Gallo Clinic and Research Center at UC San Francisco (UCSF) have shown that they ...

Neuroscience created Apr 03, 2013 | popularity 5 / 5 (11) | comments 7 | with audio podcast

Resistance to cocaine addiction may be passed down from father to son, study shows

Research from the Perelman School of Medicine at the University of Pennsylvania and Massachusetts General Hospital (MGH) reveals that sons of male rats exposed to cocaine are resistant to the rewarding effects of the drug, ...

Neuroscience created Dec 16, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Morphine and cocaine affect reward sensation differently

(Medical Xpress)—A new study by scientists in the US has found that the opiate morphine and the stimulant cocaine act on the reward centers in the brain in different ways, contradicting previous theories ...

Medical research created Oct 05, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast report

Two-drug combination has potential to fight cocaine addiction: study

A fine-tuned combination of two existing pharmaceutical drugs has shown promise as a potential new therapy for people addicted to cocaine—a therapy that would reduce their craving for the drug and blunt their symptoms ...

Addiction created Aug 08, 2012 | popularity not rated yet | comments 1 | with audio podcast

Scientists uncover molecular roots of cocaine addiction in the brain

Researchers at Johns Hopkins have unraveled the molecular foundations of cocaine's effects on the brain, and identified a compound that blocks cravings for the drug in cocaine-addicted mice. The compound, already proven safe ...

Neuroscience created May 22, 2013 | popularity not rated yet | comments 0 | with audio podcast

Cocaine vaccine passes key testing hurdle

Researchers at Weill Cornell Medical College have successfully tested their novel anti-cocaine vaccine in primates, bringing them closer to launching human clinical trials. Their study, published online by the journal Neuropsychopharmacology, used a ...

Psychology & Psychiatry created May 10, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers identify pathway that may protect against cocaine addiction

(Medical Xpress)—A study by researchers at the National Institutes of Health gives insight into changes in the reward circuitry of the brain that may provide resistance against cocaine addiction. Scientists ...

Neuroscience created Apr 16, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Discovery could yield treatment for cocaine addicts

Scientists have discovered a molecular process in the brain triggered by cocaine use that could provide a target for treatments to prevent or reverse addiction to the drug.

Neuroscience created Mar 15, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Research pinpoints, prevents stress-induced drug relapse in rats

All too often, stress turns addiction recovery into relapse, but years of basic brain research have provided scientists with insight that might allow them develop a medicine to help. A new study in the journal Neuron pinpoi ...

Neuroscience created Mar 06, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study of cocaine addiction reveals targets for treatment

Scientists at UC Santa Barbara are researching cocaine addiction, part of a widespread problem, which, along with other addictions, costs billions of dollars in damage to individuals, families, and society.

Neuroscience created Feb 13, 2013 | popularity not rated yet | comments 0 | with audio podcast

Scientists find gene interactions that make cocaine abuse death eight times more likely

Scientists have identified genetic circumstances under which common mutations on two genes interact in the presence of cocaine to produce a nearly eight-fold increased risk of death as a result of abusing the drug.

Genetics created Jan 22, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

People with low risk for cocaine dependence have differently shaped brain to those with addiction

People who take cocaine over many years without becoming addicted have a brain structure which is significantly different from those individuals who developed cocaine-dependence, researchers have discovered. New research ...

Psychology & Psychiatry created Jan 17, 2013 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Treatment for cocaine addiction targets relapse

(Medical Xpress)—What is the best intervention window for someone struggling with cocaine addiction? When he or she is in the middle of a drug binge, or after a period of abstinence when there is temptation ...

Psychology & Psychiatry created Jan 15, 2013 | popularity not rated yet | comments 0 | with audio podcast

EEG provides insight into drug-related choice in addiction, potential implications for rehabilitation

(Medical Xpress)—Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory, Stony Brook University, and collaborators may have found a way to predict drug-addicted individuals' ...

Addiction created Nov 14, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Mental fatigue impairs midbrain function in cocaine-addicted individuals, researchers find

(Medical Xpress)—Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have revealed a new connection between drug addiction and a distinct part of the brain that may govern ...

Psychology & Psychiatry created Nov 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

Cocaine

Cocaine (benzoylmethylecgonine) is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" in addition to the alkaloid suffix -ine, forming cocaine. It is both a stimulant of the central nervous system and an appetite suppressant. Specifically, it is a dopamine reuptake inhibitor, a norepinephrine reuptake inhibitor and a serotonin reuptake inhibitor, which mediates functionality of such as an exogenous DAT ligand. Because of the way it affects the mesolimbic reward pathway, cocaine is addictive.

Its possession, cultivation, and distribution are illegal for non-medicinal and non-government sanctioned purposes in virtually all parts of the world. Although its free commercialization is illegal and has been severely penalized in virtually all countries, its use worldwide remains widespread in many social, cultural, and personal settings.

For more information about Cocaine, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: brain , drug , neurons