Harvard Medical School launches major initiative to address crisis in drug development
Taking aim at the alarming slowdown in the development of new and lifesaving drugs, Harvard Medical School is launching an Initiative in Systems Pharmacology, a comprehensive strategy to transform drug discovery by convening ...
Medical research
Oct 17, 2011 |
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Incompatible assumptions common in biomedical research
Strong, incompatible views are common in biomedicine but are largely invisible to biomedical experts themselves, creating artificial barriers to effective modeling of complex biological phenomena. Researchers at the University ...
Medical research
Oct 06, 2011 |
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Novel math formula predicts success of certain cancer therapies
Carefully tracking the rate of response of human lung tumors during the first weeks of treatment can predict which cancers will undergo sustained regression, suggests a new study by researchers at the Stanford University ...
Medical research
Oct 05, 2011 |
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Researchers discover genetic risk factor for skin, prostate and brain cancers
Scientists at deCODE Genetics and academic collaborators from Iceland, The Netherlands, Spain, Denmark, Germany, Sweden, the USA, the UK and Romania today report the discovery of a variant in the sequence of the human genome ...
Genetics
Sep 25, 2011 |
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New targets for the control of HIV predicted using a novel computational analysis
A new computational approach has predicted numerous human proteins that the human immunodeficiency virus (HIV) requires to replicate itself. These discoveries "constitute a powerful resource for experimentalists who desire ...
HIV & AIDS
Sep 22, 2011 |
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Identifying correlations in electronic patient records
A new study demonstrates how text mining of electronic health records can be used to create medical term profiles of patients, which can be used both to identify co-occurrence of diseases and to cluster patients into groups ...
Other
Aug 25, 2011 |
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Researchers develop compound to block signaling of cancer-causing protein
Researchers at New York University's Department of Chemistry and NYU Langone Medical Center have developed a compound that blocks signaling from a protein implicated in many types of cancer. The compound is described in the ...
Cancer
Jul 17, 2011 |
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Multiple 'siblings' from every gene: Alternate gene reading leads to alternate gene products
A genome-wide survey by researchers at The Wistar Institute shows how our cells create alternate versions of mRNA transcripts by altering how they "read" DNA. Many genes are associated with multiple gene promoters, the researchers ...
Genetics
Jul 11, 2011 |
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Scientists discover how best to excite brain cells
(Medical Xpress) -- Oh, the challenges of being a neuron, responsible for essential things like muscle contraction, gland secretion and sensitivity to touch, sound and light, yet constantly bombarded with signals from here, ...
Medical research
Jul 08, 2011 |
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What causes brain cancer? Understanding glioblastoma at the genetic, molecular level
Glioblastoma is the most common and most lethal form of brain tumor in people. Research published in the International Journal of Computational Biology and Drug Design offers a novel way to determine what biological functi ...
Cancer
Jul 06, 2011 |
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Examining the brain as a neural information super-highway
An article demonstrating how tools for modeling traffic on the Internet and telephone systems can be used to study information flow in brain networks will be published in the open-access journal PLoS Computational Biology on 2nd ...
Neuroscience
Jun 02, 2011 |
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'Octopus' provides cancer breakthrough
A breakthrough in understanding a biological process that causes many common cancers including lung and breast cancer opens up a whole new realm of possibilities for the development of improved cancer drugs. ...
Cancer
May 13, 2011 |
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Study traces the neural wiring of a running mouse
(Medical Xpress) -- Cornell researchers have identified a group of spinal cord nerve cells that manages running in mice. In the process they have illuminated an interesting step in mouse evolution: When you're being chased ...
Neuroscience
May 12, 2011 |
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Scientists afflict computers with schizophrenia to better understand the human brain
Computer networks that can't forget fast enough can show symptoms of a kind of virtual schizophrenia, giving researchers further clues to the inner workings of schizophrenic brains, researchers at The University of Texas ...
Psychology & Psychiatry
May 05, 2011 |
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One drug, many targets: Finding molecular targets of an HIV drug used in cancer therapy
Researchers at the University of California, San Diego and Hunter College of the City University of New York (CUNY) have identified potential human molecular targets of the anti-HIV drug Nelfinavir, which may explain why ...
Medications
Apr 28, 2011 |
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