Genetics

Genes linked to schizophrenia, bipolar disorder

Broad sweeps of the human genome have exposed genetic mutations that boost the risk of the devastating yet baffling diseases of schizophrenia and bipolar disorder, according to two studies published Sunday.

Diseases, Conditions, Syndromes

Rare emerging disease claims Texas girl’s leg

A 14-year-old Texas girl was finally cured of an oft-fatal emerging disease when doctors amputated her lower leg, where the infection arose, after various antimicrobials proved ineffective. The culprit was Pythium insidiosum, ...

Psychology & Psychiatry

The Four Loko effect

The popular, formerly caffeinated, fruity alcoholic beverage, Four Loko, has been blamed for the spike in alcohol-related hospitalizations, especially throughout college campuses.

Neuroscience

A new drug to manage resistant chronic pain

Neuropathic pain, caused by nerve or tissue damage, is the culprit behind many cases of chronic pain. It can be the result of an accident or caused by a variety of medical conditions and diseases such as tumors, lupus, and ...

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Culprit

A culprit, under English law properly the prisoner at the bar, is one accused of a crime. The term is used, generally, of one guilty of an offence. In origin the word is a combination of two Anglo-French legal words, culpable: guilty, and prit or prest: Old French: ready. On the prisoner at the bar pleading not guilty, the clerk of the crown answered culpable, and states that he was ready (prest) to join issue. The words "cul. prist" were then entered on the roll, showing that issue had been joined. When French law terms were discontinued, the words were taken as forming one word addressed to the prisoner.

The formula "Culprit, how will you be tried?" in answer to a plea of "not guilty," is first found in the trial for murder of the 7th Earl of Pembroke in 1678.

 This article incorporates text from a publication now in the public domain: Chisholm, Hugh, ed (1911). Encyclopædia Britannica (11th ed.). Cambridge University Press. 

Under modern criminal law, the preferred term is defendant.

This text uses material from Wikipedia, licensed under CC BY-SA