News tagged with cultured neurons
tPA: Clot buster and brain protector
(Medical Xpress)—Ever since its introduction in the 1990s, the "clot-busting" drug tPA has been considered a "double-edged sword" for people experiencing a stroke. It can help restore blood flow to the ...
Neuroscience
May 07, 2013 |
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Structure that edits messenger RNA transcripts defective in two different forms of motor neuron diseases
Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are degenerative motor neuron diseases in which the key mutated genes are involved in RNA metabolism. This similarity suggests that a ...
Medical research
Apr 26, 2013 |
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Activation of cortical type 2 cannabinoid receptors ameliorates ischemic brain injury
A new study published in the March issue of The American Journal of Pathology suggests that cortical type 2 cannabinoid (CB2) receptors might serve as potential therapeutic targets for cerebral ischemia.
Medical research
Feb 21, 2013 |
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Excess protein linked to development of Parkinson's disease
Researchers at the University of California, San Diego School of Medicine say overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons, starting with the ...
Parkinson's & Movement disorders
Feb 07, 2013 |
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Scientists engineer the Schmallenberg virus genome to understand how to reduce disease caused by the virus
Researchers from the MRC Centre for Virus Research at the University of Glasgow in Scotland have developed methods to synthesize and change the genome of Schmallenberg virus (SBV). SBV is a recently discovered pathogen of ...
Diseases, Conditions, Syndromes
Jan 10, 2013 |
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Neurons die in Alzheimer's because of faulty cell cycle control before plaques and tangles appear
The two infamous proteins, amyloid-beta (Aβ) and tau, that characterize advanced Alzheimer's disease (AD), start healthy neurons on the road to cell death long before the appearance of the deadly plaques and tangles by working ...
Alzheimer's disease & dementia
Dec 17, 2012 |
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Rare, lethal childhood disease tracked to failure to degrade nerve cells' filaments
For the first time, a defective protein that plays a specific role in degrading intermediate filaments (IF), one of three classes of filaments that form the structure of nerve cells, has been discovered by an international ...
Medical research
Dec 17, 2012 |
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Better understanding of the cause of Alzheimer's disease: New suggestion for a possible treatment
Alzheimer's disease is the most common form of dementia, affecting over 35 million people worldwide. It is generally assumed that the clumping of beta-amyloid (Aß) protein causes neuronal loss in patients. Medication focuses ...
Alzheimer's disease & dementia
Dec 14, 2012 |
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Dopamine not about pleasure (anymore)
(Medical Xpress)—To John Salamone, professor of psychology and longtime researcher of the brain chemical dopamine, scientific research can be very slow-moving.
Neuroscience
Dec 03, 2012 |
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Researchers report potential new treatment to stop Alzheimer's disease
Last March, researchers at UCLA reported the development of a molecular compound called CLR01 that prevented toxic proteins associated with Parkinson's disease from binding together and killing the brain's neurons.
Alzheimer's disease & dementia
Nov 15, 2012 |
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Hunting neuron killers in Alzheimer's and traumatic brain injury
Levels of the protein appoptosin in the brain skyrocket in Alzheimer's disease and traumatic brain injury. Appoptosin is known for helping the body make heme, the molecule that carries iron in the blood. In a study published ...
Neuroscience
Nov 09, 2012 |
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The brain's circuit diagram: New method facilitates the mapping of connections between neurons
(Medical Xpress)—The human brain accomplishes its remarkable feats through the interplay of an unimaginable number of neurons that are interconnected in complex networks. A team of scientists has now developed ...
Neuroscience
Oct 18, 2012 |
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Modified tPA could be effective stroke treatment without bleeding risk
Even when its clot-dissolving powers are removed, the stroke drug tPA can still protect brain cells from the loss of oxygen and glucose induced by a stroke, researchers have discovered.
Neuroscience
Jul 17, 2012 |
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Boundary stops molecule right where it needs to be
A molecule responsible for the proper formation of a key portion of the nervous system finds its way to the proper place not because it is actively recruited, but instead because it can't go anywhere else.
Neuroscience
May 24, 2012 |
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New technology could inspire brain implant for detecting and treating seizures
(Medical Xpress) -- Tiny electrodes have been coated with a drug-loaded polymer in an attempt to design an implant capable of detecting a number of neurological symptoms, such as those associated with an epileptic ...
Medical research
Jun 02, 2011 |
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