Diseases, Conditions, Syndromes

Macrophages as drivers of an opportunistic infection

The opportunistic bacterium Burkholderia cenocepacia is feared by cystic fibrosis patients and is emerging in hospital-acquired infections. An international study sheds new light on the infection mechanism of this opportunistic ...

Medical research

Clinical trials pave way to new cystic fibrosis drug

Imagine breathing through only a tiny straw. That is what life is like for people with cystic fibrosis, which includes about 30,000 people in the United States, making cystic fibrosis the most common lethal genetic disease ...

Genetics

Pathogen demonstrates genome flexibility in cystic fibrosis

Chronic lung infections can be devastating for patients with cystic fibrosis (CF), and infection by Burkholderia cenocepacia, one of the most common species found in cystic fibrosis patients, is often antibiotic resistant. ...

Inflammatory disorders

Researchers find new potential route to treat asthma

Researchers at the UNC School of Medicine believe they have isolated a protein that, when missing or depleted, can cause airway constriction, production of mucus, chest tightness, and difficulty breathing for the 334 million ...

Medical research

First stem cell study in the world for cystic fibrosis opens

A 39-year-old man with cystic fibrosis (CF) made history by becoming the first person in the world to receive human adult stem cells in a new research study that researchers hope will someday lead to the development of a ...

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