Genetics

Editing RNA to fix protein problems in cystic fibrosis

The process of generating proteins from genes is akin to a factory, where workers follow a set of instructions that, ideally, are effective and clear. But for some people who suffer from cystic fibrosis (CF), one of their ...

Neuroscience

A cure for Alzheimer's is taking longer than expected; here's why

In her latest research paper, published in the Journal of Molecular Neuroscience, Anne Robinson, Head of Carnegie Mellon's Department of Chemical Engineering, explains why understanding the progression of neurodegeneration ...

Diseases, Conditions, Syndromes

Partial bone marrow transplant 'rescues' mice with cystic fibrosis

Scientists at La Jolla Institute for Immunology (LJI) have found they can dramatically improve survival of mice with cystic fibrosis through a partial bone marrow transplant. Their new study in the Journal of Immunology shows ...

Diseases, Conditions, Syndromes

Cystic fibrosis faithfully modeled in a human Lung Airway Chip

The inherited progressive disorder cystic fibrosis (CF) causes severe damage to the lungs, and other tissues in the body by affecting the cells that produce mucus, sweat, and digestive juices. In individuals carrying mutations ...

Diseases, Conditions, Syndromes

Lower airways are distinct in cystic fibrosis even at younger ages

In the largest study of its kind, researchers found that the lower airways in children with cystic fibrosis (CF) have a higher burden of infection, more inflammation and lower diversity of microorganisms, compared to children ...

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