A new study published in Science Translational Medicine has found that in women with BRCA gene mutations, having a high body mass index (BMI) is linked to more DNA damage in breast cells. Specifically, the study discovered ...
In hepatic steatosis, hepatocytes "die," resulting in liver damage. Severe steatosis increases hepatocellular deaths, thus aggravating liver damage. The mechanism is unclear. Using mice, we show that mild steatosis causes ...
Feb 15, 2023
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E-cigarettes—used regularly by more than 10% of U.S. teens and more than 3% of adults—were once pitched as a healthy alternative to tobacco cigarettes. But research increasingly links the use of e-cigarettes, or vaping, ...
Feb 14, 2023
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Melbourne researchers have improved our understanding of how the immune system is regulated to prevent disease, identifying a previously unknown role of 'natural killer' (NK) immune cells.
Feb 10, 2023
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A mutant or damaged gene may be a cause of a severe, mysterious form of nonalcoholic fatty liver disease, University of Illinois Urbana-Champaign researchers have found. Mice and human liver cells lacking the SRSF1 gene show ...
Feb 9, 2023
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A team of medical scientists working at the University of Pennsylvania's Perelman School of Medicine has used single-nucleus RNA sequencing to isolate those mouse liver cells cells that push the progression of nonalcoholic ...
UConn Assistant Professor of Immunology Zhichao Fan specializes in the molecular mechanics of inflammation, specifically the mechanism that activates the adhesion of white blood cells or leukocytes in inflammation associated ...
Feb 6, 2023
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A study led by Consejo Superior de Investigaciones Científicas (CSIC) has demonstrated the efficiency of an ultrasound radiation-based therapy on the inhibition of cancer cell motion in pancreas cancer models. This work, ...
Jan 30, 2023
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The first comprehensive study of somatic mutations in normal human small intestine has been conducted by researchers at the Wellcome Sanger Institute and their collaborators. The findings revealed that an enzyme named APOBEC1 ...
Jan 27, 2023
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Interleukin (IL)-11 is produced by inflammatory fibroblasts, one of the stromal cells, during acute colitis. Researchers at Toho University Japan found that IL-11 ameliorated acute colitis in mouse models. The IL-11 production ...
Jan 17, 2023
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