News tagged with deep vein thrombosis
(Medical Xpress)—Scientists have identified a group of small molecules that interfere with the activity of a compound that initiates multiple steps in blood clotting, including those that lead to the obstruction of veins ...
Medical research Nov 06, 2012 | 5 / 5 (3) | 0 |
(HealthDay)—The new anti-clotting drug apixaban (Eliquis) appears to help prevent potentially fatal blood clots in patients with deep vein thrombosis (DVT), a new Italian study finds.
Medications Dec 10, 2012 | 5 / 5 (3) | 0 |
A new risk prediction tool can identify patients at high risk of serious blood clots (known as venous thromboembolism) who might need preventative treatment, says a study published in the British Medical Journal today.
Diseases, Conditions, Syndromes Aug 17, 2011 | 5 / 5 (2) | 0
A new type of anti-clotting drug called semuloparin has been found to reduce the development of potentially fatal blood clots in the veins that often occur in cancer patients, doctors at Duke Cancer Institute and elsewhere ...
Cancer Jun 07, 2011 | 5 / 5 (1) | 0 |
(AP) -- New advice for pregnant women: If you're getting a C-section, special inflating boots strapped on your legs may lower the risk of a blood clot.
Health Aug 29, 2011 | 5 / 5 (1) | 0
Blood clots in the legs or lungs (deep vein thrombosis or pulmonary embolism) kill an American about every 5 minutes. Adopting seven simple lifestyle steps could help reduce your risk of these potentially deadly blood clots, ...
Cardiology May 02, 2013 | 5 / 5 (1) | 0
(Medical Xpress)—A gene associated with both protection against bacterial infection and excessive blood clotting could offer new insights into treatment strategies for deep-vein thrombosis—the formation ...
Genetics May 08, 2013 | 5 / 5 (1) | 0 |
(Medical Xpress)—Low-dose aspirin is a cheap and effective way to prevent potentially deadly blood clots in the leg or the lungs in patients who have had a previous blood clot, a new study shows.
Diseases, Conditions, Syndromes Nov 05, 2012 | 4 / 5 (1) | 0 |
(HealthDay)—The Society for Vascular Medicine (SVM) has published "Five Things Physicians and Patients Should Question" in vascular medicine, a list of five tests and procedures that are commonly used but ...
Cardiology Feb 26, 2013 | 4 / 5 (1) | 0
A team of global scientists, led by researchers at Intermountain Medical Center in Salt Lake City, has developed a safer and more accurate way to administer warfarin, one of the most commonly prescribed but also potentially ...
Medical research Feb 29, 2012 | 3 / 5 (1) | 0 |
Deep vein thrombosis
In medicine, deep vein thrombosis (also known as deep-vein thrombosis or deep venous thrombosis and usually abbreviated as DVT) is the formation of a blood clot ("thrombus") in a deep vein. It is a form of thrombophlebitis (inflammation of a vein with clot formation).
Deep vein thrombosis commonly affects the leg veins (such as the femoral vein or the popliteal vein) or the deep veins of the pelvis. Occasionally the veins of the arm are affected (if spontaneous, this is known as Paget-Schrötter disease). A DVT can occur without symptoms, but in many cases the affected extremity will be painful, swollen, red, warm and the superficial veins may be engorged. The most serious complication of a DVT is that the clot could dislodge and travel to the lungs, which is called a pulmonary embolism (PE). DVT is a medical emergency, present in the lower extremity there is 3% chance of a PE killing the patient. A late complication of DVT is the post-phlebitic syndrome, which can manifest itself as edema, pain or discomfort and skin problems.
According to Virchow's triad, venous thrombosis occurs via three mechanisms: decreased flow rate of the blood, damage to the blood vessel wall and an increased tendency of the blood to clot (hypercoagulability). Several medical conditions can lead to DVT, such as compression of the veins, physical trauma, cancer, infections, certain inflammatory diseases and specific conditions such as stroke, heart failure or nephrotic syndrome. There are several factors which can increase a person's risk for DVT, including surgery, hospitalization, immobilization (such as when orthopedic casts are used, or during long-haul flights, leading to economy class syndrome), smoking, obesity, age, certain drugs (such as estrogen or erythropoietin) and inborn tendencies to form clots known as thrombophilia (for example, in carriers of factor V Leiden). Women have an increased risk during pregnancy and in the postnatal period.
The most commonly used tests for the diagnosis of DVT are a blood test called D-dimers and doppler ultrasound of the affected veins. Sometimes, further testing is required to find the cause of the DVT. In specific cases, an attempt can be made to break down the clot (using thrombolytic agents). To prevent further accrual and formation of new clots with a risk of pulmonary embolism, anticoagulation (blood thinners) is advised (if not possible, an inferior vena cava filter may be used). Prevention of DVT is advised in many medical and surgical inpatients using anticoagulants, graduated compression stockings (also known as thromboembolic deterrent stockings) or intermittent pneumatic compression devices.
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