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Langerhans cells migrate to their final destination in multiple waves at different stages of embryonic development

As our primary interface with the outside world, the skin needs to be able to protect itself against infectious threats. Specialized cells known as Langerhans cells (LCs) (see image) are an essential component ...

Medical research created Aug 29, 2012 | popularity not rated yet | comments 0

Video shows the traffic inside a brain cell

Using bioluminescent proteins from a jellyfish, a team of scientists has lit up the inside of a neuron, capturing spectacular video footage that shows the movement of proteins throughout the cell.

Neuroscience created Aug 22, 2012 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Preschool within lymphatic vessels

Not only infants crawl. ETH researchers have shown that so-called dendritic cells, important cells of the immune system, use a similar mode of movement more often than previously assumed. The scientists us ...

Medical research created Aug 09, 2012 | popularity not rated yet | comments 0

Triangles guide the way for live neural circuits in a dish

Korean scientists have used tiny stars, squares and triangles as a toolkit to create live neural circuits in a dish.

Neuroscience created Jul 19, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists discover dendritic cells key to activating human immune responses

Scientists at A*STAR’s Singapore Immunology Network (SIgN), in collaboration with Newcastle University, UK, the Singapore Institute of Clinical Sciences and clinicians from multiple hospitals in Singapore, have identified ...

Immunology created Jul 16, 2012 | popularity not rated yet | comments 0

Branching out: A mathematical law of dendritic connectivity

(Medical Xpress) -- That the brain is evolution at its finest is perhaps best demonstrated by the beauty, complexity and diversity of dendrites – tree-like structures that form neural circuits by connecting ...

Neuroscience created Jun 28, 2012 | popularity 4.9 / 5 (10) | comments 7 | with audio podcast feature

Think global, act local: New roles for protein synthesis at synapses

(Medical Xpress) -- How do we build a memory in the brain? It is well known that for animals (and humans) new proteins are needed to establish long-term memories. During learning information is stored at the synapses, the ...

Neuroscience created May 10, 2012 | popularity not rated yet | comments 0 | with audio podcast

Research shows how PCBs promote dendrite growth, may increase autism risk

New research from UC Davis and Washington State University shows that PCBs, or polychlorinated biphenyls, launch a cellular chain of events that leads to an overabundance of dendrites — the filament-like projections ...

Autism spectrum disorders created Apr 25, 2012 | popularity 4 / 5 (3) | comments 0 | with audio podcast

Mechanism of HIV spread has potential for future drug therapy

A new understanding of the initial interactions of human immunodeficiency virus type 1 (HIV-1) and dendritic cells is described by Boston University School of Medicine (BUSM) researchers in a study currently featured in the ...

HIV & AIDS created Apr 23, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study: Epstein Barr virus protects against autoimmune disease

To the surprise of investigating researchers, an animal model of Epstein Barr virus protected lupus-prone mice against development of the autoimmune disease. Earlier work had suggested that EBV might promote the development ...

Immunology created Apr 02, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Immune cells with a killer instinct: Tried-and-tested anti-tumour drug displays new effect

Imiquimod, a drug used to treat skin cancer, has been shown to have a previously unknown effect on immune cells. The drug transforms cells known as dendritic cells into "tumour killers" that attack the tumour ...

Immunology created Mar 26, 2012 | popularity not rated yet | comments 0

Scientists identify novel pathway for T-cell activation in leprosy

UCLA researchers pinpointed a new mechanism that potently activates T-cells, the group of white blood cells that play a major role in fighting infections.

Medical research created Mar 25, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Microneedle vaccine patch boosts flu protection through robust skin cell immune response

Recent research found that microneedle vaccine patches are more effective at delivering protection against influenza virus in mice than subcutaneous or intramuscular inoculation. A new, detailed analysis of the early immune ...

Immunology created Mar 06, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers find sarcoma tumor immune response with combination therapy

A team of 18 researchers at Moffitt Cancer Center in Tampa, Fla., have found that treating high-risk, soft tissue sarcoma patients with a combination of implanted dendritic cells (immune system cells) and fractionated external ...

Cancer created Mar 01, 2012 | popularity 5 / 5 (1) | comments 0

Traitorous immune cells promote sudden ovarian cancer progression

Aggressive ovarian tumors begin as malignant cells kept in check by the immune system until, suddenly and unpredictably, they explode into metastatic cancer. New findings from scientists at The Wistar Institute demonstrate ...

Cancer created Feb 20, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast