News tagged with dendritic cells

Related topics: cells · white blood cells · immune response · immune system · immune cells

Skin microbes trigger specific immune responses

New research in mice shows that the immune system in the skin develops distinct responses to the various microbes that naturally colonize the skin, referred to as commensals. A team led by scientists at the National Institute ...

Jan 05, 2015
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Why CLL there are often relapses after treatment

Chronic lymphocytic leukemia (CLL) is among the most frequent leukemias affecting adults in Western countries. It usually occurs in older patients, does not cause any symptoms for a long time and is often only discovered ...

Dec 05, 2014
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The STING of radiation

A team of researchers led by Ludwig Chicago's Yang-Xin Fu and Ralph Weichselbaum has uncovered the primary signaling mechanisms and cellular interactions that drive immune responses against tumors treated with radiotherapy. ...

Nov 20, 2014
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Dendritic cell

Dendritic cells (DCs) are immune cells that form part of the mammalian immune system. Their main function is to process antigen material and present it on the surface to other cells of the immune system, thus functioning as antigen-presenting cells.

Dendritic cells are present in small quantities in tissues that are in contact with the external environment, mainly the skin (where there is a specialized dendritic cell type called Langerhans cells) and the inner lining of the nose, lungs, stomach and intestines. They can also be found in an immature state in the blood. Once activated, they migrate to the lymphoid tissues where they interact with T cells and B cells to initiate and shape the adaptive immune response. At certain development stages they grow branched projections, the dendrites, that give the cell its name. However, these do not have any special relation with neurons, which also possess similar appendages. Immature dendritic cells are also called veiled cells, in which case they possess large cytoplasmic 'veils' rather than dendrites.

This text uses material from Wikipedia, licensed under CC BY-SA

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