No one knows what makes a mild dengue viral infection morph into a severe and sometimes deadly dengue hemorrhagic fever/dengue shock syndrome. Experts previously believed the likely cause was ramped up activity of T cells, ...
Dec 24, 2019
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Researchers led by Duke-NUS Medical School have discovered that tryptase, an enzyme in human cells that acts like scissors to cut up nearby proteins, is responsible for blood vessel leakage in severe dengue hemorrhagic fever. ...
Aug 27, 2019
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To cross the placenta, Zika virus may hijack the route by which acquired immunity is transferred from mother to fetus, new research suggests.
Nov 14, 2018
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(Medical Xpress)—A team of researchers from the U.S. and Nicaragua has found evidence that suggests people infected a second time by the dengue virus may experience a more severe form of dengue fever if their antibody levels ...
Scientists at the University of California, Berkeley, have identified a key culprit responsible for the fluid loss and resulting shock that are the hallmark of severe - and potentially fatal - dengue virus infections.
Sep 9, 2015
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Researchers at Vanderbilt University and the National University of Singapore have determined the structure of a human monoclonal antibody which, in an animal model, strongly neutralizes a type of the potentially lethal dengue ...
Jul 2, 2015
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A team of scientists from the University of North Carolina at Chapel Hill and Vanderbilt University have pinpointed the region on dengue virus that is neutralized in people who overcome infection with the deadly pathogen. ...
Apr 11, 2012
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The Philippines said Thursday that some of the 14 children who died after receiving a controversial vaccine showed signs of "severe dengue", as investigators probe the drug whose use was suspended due to health concerns.
Jan 11, 2018
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For a long time, a dengue vaccine was the holy grail in dengue research. Now that a dengue vaccine is finally on the market (Sanofi's Dengvaxia), other issues have arisen, such as what happens in the babies of vaccinated ...
Dec 22, 2017
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Why mosquito-borne dengue virus causes more severe disease in some individuals, including hemorrhagic fever with or without shock, remains controversial and researchers are focusing on the factors related to the interaction ...
Jun 12, 2017
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