Diabetes

NASH-linked changes impact metformin pharmacokinetics

(HealthDay)—Nonalcoholic steatohepatitis (NASH)-associated changes in liver function affect kidney transporter expression and metformin pharmacokinetics, according to an experimental study published online May 27 in Diabetes ...

Medical research

Molecular link found between high glucose, metabolic disease

Scientists at Johns Hopkins say they've discovered a cause-and-effect link between chronic high blood sugar and disruption of mitochondria, the powerhouses that create the metabolic energy that runs living cells. The discovery, ...

Diabetes

Study reveals how FOXO1 slows diabetic wound healing

A protein that normally fosters tissue repair instead acts to inhibit healing when sugar levels are high, according to a study in The Journal of Cell Biology. The role reversal helps explain why wounds heal slowly in people ...

Medical research

Cancer drug shows promise for treating stroke

A University of Victoria neuroscientist has discovered that a cancer drug may improve recovery rates for diabetic patients who have suffered a stroke.

Overweight & Obesity

Special microbes make anti-obesity molecule in the gut

Microbes may just be the next diet craze. Researchers have programmed bacteria to generate a molecule that, through normal metabolism, becomes a hunger-suppressing lipid. Mice that drank water laced with the programmed bacteria ...

Diabetes

Erectile dysfunction drug relieves nerve damage in diabetic mice

New animal studies at Henry Ford Hospital found that sildenafil, a drug commonly used to treat erectile dysfunction, may be effective in relieving painful and potentially life-threatening nerve damage in men with long-term ...

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