Oncology & Cancer

Cell signaling targets in leukemia

Mutations in the enzyme IDH (isocitrate dehydrogenase) are found in 15–20% of acute myeloid leukemia (AML) cases. IDH mutations have been shown to impact cellular differentiation and DNA and histone methylation, but little ...

Oncology & Cancer

Converting glioma cells into neurons may treat glioblastoma

Gliomas are the most common primary brain tumors in adults. Among them, the high-grade glioblastomas (GBMs) are particularly known to be notoriously aggressive and invasive, which makes it challenging to treat them. The disease ...

Arthritis & Rheumatism

Inflammation at IP thumb joint common in psoriatic arthritis

(HealthDay)—Patients with psoriatic arthritis (PsA) more often have inflammation at the interphalangeal (IP) joint of the thumb compared to those with undifferentiated inflammatory arthritis (UIA), according to a study ...

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