News tagged with disease models


How chronic stress accelerates Alzheimer's disease

Why does chronic stress lead to increased risk for dementia? The answer may lie in the elevation of stress steroids that is seen in the brain during stress, Sara K. Bengtsson suggests in the thesis she is ...

Alzheimer's disease & dementia created Mar 14, 2013 | popularity 5 / 5 (1) | comments 0

Team finds mechanism that regulates production of energy-burning brown fat

Joslin scientists have discovered a mechanism that regulates the production of brown fat, a type of fat which plays an important role in heat production and energy metabolism. The findings, which appear in the upcoming issue ...

Medical research created Mar 13, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Normal prion protein regulates iron metabolism

An iron imbalance caused by prion proteins collecting in the brain is a likely cause of cell death in Creutzfeldt-Jakob disease (CJD), researchers at Case Western Reserve University School of Medicine have found.

Alzheimer's disease & dementia created Mar 13, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Protein implicated in lupus promotes disease progression by distinct mechanisms in different immune cells

Patients with systemic lupus erythematosus (SLE) come under attack by their immune system, producing 'autoantibodies' that inflict damage throughout the body. Antibodies normally target foreign proteins, ...

Immunology created Mar 13, 2013 | popularity not rated yet | comments 0

Study reveals therapeutic targets to alter inflammation, type 2 diabetes

New research from Boston University School of Medicine (BUSM) reveals that B cells regulate obesity-associated inflammation and type 2 diabetes through two specific mechanisms. The study, published in the Proceedings of th ...

Inflammatory disorders created Mar 12, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Women live longer, but have a lower quality of life

To mark International Women's Day on 8th March 2013, the Institute of Gender Medicine at the MedUni Vienna has presented an alarming result obtained from gender-specific research. According to recent studies, ...

Health created Mar 11, 2013 | popularity not rated yet | comments 0

Research illuminates molecular mechanism for why stimulating environment may protect against Alzheimer's disease

"Use it or lose it." The saying could apply especially to the brain when it comes to protecting against Alzheimer's disease. Previous studies have shown that keeping the mind active, exercising and social interactions may ...

Alzheimer's disease & dementia created Mar 06, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Demystifying addiction: An online educational resource

A new free online educational resource has been developed by health researchers from the University of Otago, Wellington to help people learn about addiction directly from those who have experienced it.

Addiction created Mar 06, 2013 | popularity not rated yet | comments 0

Age-related dementia may begin with neurons' inability to dispose of unwanted proteins

A team of European scientists from the University Medical Center Hamburg-Eppendorf (UKE) and the Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) at the University of Cologne in ...

Alzheimer's disease & dementia created Mar 05, 2013 | popularity 5 / 5 (1) | comments 0

Proteins with mutations in 'prion-like' segments considered candidates for inherited forms of ALS

A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders. James Shorter, Ph.D., assistant professor of Biochemistry and Biophysics at the Perelman ...

Medical research created Mar 03, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New model could lead to improved treatment for early stage Alzheimer's

Researchers at the University of Florida and The Johns Hopkins University have developed a line of genetically altered mice that model the earliest stages of Alzheimer's disease. This model may help scientists identify new ...

Alzheimer's disease & dementia created Feb 28, 2013 | popularity not rated yet | comments 0 | with audio podcast

Simple method devised for determining atrial fibrillation risk in women

Atrial fibrillation is the most common type of abnormal heart rhythm, affecting 2.5 million Americans. If left undetected or untreated, atrial fibrillation can lead to stroke. Determining who is at increased risk for atrial ...

Cardiology created Feb 26, 2013 | popularity not rated yet | comments 0

Drug delivery strategy eliminates myotonia symptoms in mice with myotonic dystrophy

By targeting the specific mutation that causes the hereditary neuromuscular disease myotonic dystrophy, it is possible to neutralize the mutant RNA toxicity and minimize or even eliminate the disabling symptoms ...

Diseases, Conditions, Syndromes created Feb 22, 2013 | popularity 5 / 5 (1) | comments 0

Unlimited source of human kidney cells: Applications include in vitro toxicology, disease models, regenerative medicine

Researchers at the Institute of Bioengineering and Nanotechnology (IBN) have successfully generated human kidney cells from human embryonic stem cells in vitro. Specifically, they produced the renal cells under artificial ...

Medical research created Feb 21, 2013 | popularity not rated yet | comments 0

Using transportation data to predict pandemics

In a world of increasing global connections, predicting the spread of infectious diseases is more complicated than ever. Pandemics no longer follow the patterns they did centuries ago, when diseases swept through populations ...

Diseases, Conditions, Syndromes created Feb 16, 2013 | popularity not rated yet | comments 0