Scientists develop drug that slows Alzheimer's in mice
A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer's disease in aged mice following short-term treatment. The findings, ...
Alzheimer's disease & dementia
May 13, 2013 |
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Scientists identify early predictors of disease progression which could speed Huntington's disease drug trials
Scientists have identified a set of tests that could help identify whether and how Huntington's disease (HD) is progressing in groups of people who are not yet showing symptoms. The latest findings from the TRACK-HD study, ...
Neuroscience
May 08, 2013 |
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Ambrisentan not effective in idiopathic pulmonary fibrosis
(HealthDay)—The endothelin A receptor-selective antagonist ambrisentan is not effective for reducing the rate of idiopathic pulmonary fibrosis (IPF) progression, according to a study published in the May ...
Diseases, Conditions, Syndromes
May 07, 2013 |
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Large-scale genetic study defines relationship between primary sclerosing cholangitis and other autoimmune diseases
For the first time, scientists show that a leading cause of liver transplant, primary sclerosing cholangitis (PSC), is a distinct disease from inflammatory bowel disease, opening up new avenues for specific PSC treatments.
Genetics
Apr 21, 2013 |
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Scientists much closer to developing screening test for early detection of Alzheimer's disease
They identified blood-based biological markers that are associated with the build up of a toxic protein in the brain which occurs years before symptoms appear and irreversible brain damage has occurred.
Alzheimer's disease & dementia
May 01, 2013 |
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Scientists solve mystery of nerve disease genes
For several years, scientists have been pondering a question about a genetic disease called Charcot-Marie-Tooth (CMT) disease type 2D: how can different types of mutations, spread out across a gene, produce ...
Medical research
Jul 04, 2011 |
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Cell response to new coronavirus unveils possible paths to treatments
NIH-supported scientists used lab-grown human lung cells to study the cells' response to infection by a novel human coronavirus (called nCoV) and compiled information about which genes are significantly disrupted ...
Diseases, Conditions, Syndromes
Apr 30, 2013 |
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Unusual suspect: Scientists find 'second fiddle' protein's role in Type 2 diabetes
A team of researchers at the Johns Hopkins Children's Center has found that a protein long believed to have a minor role in type 2 diabetes is, in fact, a central player in the development of the condition that affects nearly ...
Diabetes
Apr 11, 2013 |
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Discovery may shed light on why some HIV-positive patients have more virus
(Medical Xpress)—Biologists at UC San Diego have unraveled the anti-viral mechanism of a human gene that may explain why some people infected with HIV have much higher amounts of virus in their bloodstreams ...
HIV & AIDS
Sep 24, 2012 |
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New drug protects neurons in Parkinson's patients
(Medical Xpress)—Scientists at Emory University School of Medicine have identified a compound that boosts levels of a survival factor in neurons threatened by Parkinson's disease.
Parkinson's & Movement disorders
Sep 05, 2012 |
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Newly identified tumor suppressor provides therapeutic target for prostate cancer
Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have identified how an enzyme called PKCζ suppresses prostate tumor formation. The finding, which also describes a molecular chain ...
Cancer
Apr 01, 2013 |
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Study shines light on how stress circuits learn
Researchers at the University of Calgary's Hotchkiss Brain Institute have discovered that stress circuits in the brain undergo profound learning early in life. Using a number of cutting edge approaches, including ...
Neuroscience
Apr 07, 2013 |
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Ingredient in new MS drug linked to serious brain disease
(HealthDay)—The active ingredient in a drug that's expected to become a popular treatment for multiple sclerosis has been linked to four European cases of a rare but sometimes fatal brain disease called ...
Medications
Apr 24, 2013 |
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Lack of oxygen in cancer cells leads to growth and metastasis
(Medical Xpress)—It seems as if a tumor deprived of oxygen would shrink. However, numerous studies have shown that tumor hypoxia, in which portions of the tumor have significantly low oxygen concentrations, ...
Cancer
Sep 13, 2012 |
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Transition in cell type parallels treatment response, disease progression in breast cancer
A process that normally occurs in developing embryos – the changing of one basic cell type into another – has also been suspected of playing a role in cancer metastasis. Now a study from Massachusetts General Hospital ...
Cancer
Jan 31, 2013 |
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