Medical research

Unexpected hope for DNA damage-related diseases

DNA damage in cells can lead to genetic diseases and a variety of cancers. To repair any damage, a process in our bodies flags repair proteins and recruits them to the damaged site. This process is called ADP-ribosylation ...

Medical research

Runaway mitochondria cause telomere damage in cells

Researchers at UPMC Hillman Cancer Center provide the first concrete evidence for the long-held belief that sick mitochondria pollute the cells they're supposed to be supplying with power.

Oncology & Cancer

Major mutation pattern in cancer occurs in bursts

Researchers have created a huge resource for investigating the biological mechanisms that cause cancer. The scientists from the Wellcome Sanger Institute and their collaborators identified which patterns of DNA damage—mutational ...

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