News tagged with dna methylation

Epigenetic changes may explain chronic kidney disease

The research of physician-scientist Katalin Susztak, MD, PhD, associate professor of Medicine in the Renal Electrolyte and Hypertension Division, at the Perelman School of Medicine, University of Pennsylvania, strives to ...

Nov 22, 2013
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Aging impacts epigenome in human skeletal muscle

Our epigenome is a set of chemical switches that turn parts of our genome off and on at strategic times and locations. These switches help alter the way our cells act and are impacted by environmental factors including diet, ...

Nov 20, 2013
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Linking risk factors and disease origins in breast cancer

Researchers from the Geisel School of Medicine at Dartmouth have found that epigenetic changes to DNA are associated with aging in disease-free breast tissues and are further altered in breast tumors. Epigenetic changes describe ...

Nov 20, 2013
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Methylation linked to metabolic disease

(Medical Xpress)—In the first in-depth analysis of DNA methylation in fat, a process that affects the regulation of genes, researchers have linked regions of methylation to metabolic traits such as high ...

Nov 11, 2013
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Biomarker may help predict aggressive cancers

For children with central nervous system cancers, the presence of a specific genetic modification—hypermethylation of the TERT promoter—may help predict tumor progression and patient survival, according to results presented ...

Nov 05, 2013
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Blood test reveals skin cancer spread

A simple blood test could be used to identify patients whose melanoma – the most serious form of skin cancer – has started to spread to other parts of the body, according to research presented at the ...

Nov 04, 2013
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Genes protect themselves against being silenced

Harvard Stem Cell Institute (HSCI) researchers have settled a century-old debate over whether occurrence of DNA methylation acts to silence gene expression, or if genes are turned off by other means before ...

Oct 10, 2013
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Study of 'sister' stem cells uncovers new cancer clue

Scientists have used a brand new technique for examining individual stem cells to uncover dramatic differences in the gene expression levels – which genes are turned 'up' or 'down'– between apparently identical 'sister' ...

Sep 26, 2013
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Lifestyle influences metabolism via DNA methylation

An unhealthy lifestyle leaves traces in the DNA. These may have specific effects on metabolism, causing organ damage or disease. Scientists of Helmholtz Zentrum München have now identified 28 DNA alterations associated with ...

Sep 20, 2013
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