Oncology & Cancer
Cancer study shows how chemicals cause complex cell mutations
Fresh insights into why some harmful substances are so efficient at causing cancer could aid the quest for better treatments.
Jun 24, 2020
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189
News tagged with dna mutations
Genetics
The rate we acquire genetic mutations could help predict lifespan, fertility
Differences in the rate that genetic mutations accumulate in healthy young adults could help predict remaining lifespan in both sexes and the remaining years of fertility in women, according to University of Utah Health scientists. ...
Jun 19, 2020
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175
Genetics
New method created for identifying genes behind brain tumors
Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma—a malignant brain tumor with a very poor prognosis. The ...
Jun 9, 2020
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260
Oncology & Cancer
Scientists reveal how mutations in metabolism can drive cancers
Our cells have several ways to repair DNA that breaks when the cells divide. However, genetic mutations can disable these DNA repair mechanisms, destabilize the cells, and trigger cancer. In a paper published today in the ...
Jun 4, 2020
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172
Oncology & Cancer
Platinum-based chemo may improve survival for some metastatic pancreatic cancer patients
Patients with metastatic pancreatic cancer who had germline or somatic mutations in DNA repair genes had better clinical outcomes after platinum-based chemotherapy, as compared with patients without these mutations, according ...
May 22, 2020
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1
Oncology & Cancer
Potentially cancerous cells kept in check by competitive neighbours, study of oesophagus finds
The expansion of 'mutant' cells that could lead to cancer is often kept in check by their neighbours, research from the Wellcome Sanger Institute, the University of Cambridge and their collaborators has found. The team discovered ...
May 19, 2020
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88
Medical research
New research into stem cell mutations could improve regenerative medicine
Research from the University of Sheffield has given new insight into the cause of mutations in pluripotent stem cells and potential ways of stopping these mutations from occurring.
May 14, 2020
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10
Oncology & Cancer
New targeted agent produces considerable responses in patients with uterine cancer
In its first clinical trial in patients with a hard-to-treat form of uterine cancer, a targeted drug that subjects tumor cells to staggering levels of DNA damage caused tumors to shrink in nearly one-third of patients, investigators ...
Apr 24, 2020
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2
Genetics
New tool helps gather useful genetic information obtained from blood, skin tissues
DNA sequencing is becoming a more commonplace method for detecting diseases and improving precision medicine. Because DNA sequencing does not detect all possible disease-causing mutations, RNA sequencing is often used to ...
Apr 8, 2020
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70
Oncology & Cancer
3-D genetic structure in blood cancer important beyond DNA code changes
Children with aggressive blood cancers have differences—not just in the DNA code of their blood cells—but also in the heavily twisted protein superstructure that controls access to genes.
Mar 23, 2020
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