Mutations, which occur continuously in every cell of our bodies, are a key contributor to cancer, aging, and neurodegeneration. While exposure to mutagenic chemicals, or mistakes in cellular processes during DNA replication ...
Jan 10, 2024
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Children with bilateral Wilms tumor have a tumor in each of their kidneys—a condition that strongly suggests an underlying genetic or epigenetic predisposition driving the disease. Scientists at St. Jude Children's Research ...
Dec 18, 2023
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Scientists at the Ontario Institute for Cancer Research (OICR) have uncovered one way tobacco smoking causes cancer and makes it harder to treat by undermining the body's anti-cancer safeguards.
Nov 3, 2023
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A pioneering study led by Professor Ashok Venkitaraman from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore and Dr. Mona Shehata from the University of Cambridge (UK) has ...
Nov 2, 2023
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Researchers at Baylor College of Medicine have developed a new compound called d16 that can reduce tumor growth and overcome therapeutic resistance in mutant p53-bearing cancers in the lab. The findings, published in the ...
Sep 27, 2023
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Evidence suggests that allogenic hematopoietic cell transplantation (HCT) improves overall survival in patients with myelodysplastic syndrome (MDS), a serious blood disorder, when compared with best available supportive care. ...
Aug 23, 2023
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Each cell in the body stores its genetic information in DNA in a stable and protected form that is readily accessible for the cell to carry on its activities. Nevertheless, mutations—changes in genetic information—occur ...
Aug 3, 2023
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While cancers often originate from mutations and other alterations of cells' DNA, researchers in the Bernstein Laboratory at Dana-Farber and the Broad Institute of MIT and Harvard have found that gliomas—incurable brain ...
Jul 25, 2023
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In a new paper published today in Nature, researchers at the Francis Crick Institute have outlined the structure and function of a protein complex that is required to repair damaged DNA and protect against cancer.
Jun 21, 2023
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A new family of DNA elements which control the activation of certain genes known to cause a rare disease known as MSL3 syndrome in children has been identified.
Jun 12, 2023
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