Mice inhabiting an area known for its high concentration of asbestos-contaminated dust, have a higher level of genetic somatic mutations, compared with other regions where asbestos pollution levels are lower. This has been ...
Jun 15, 2011
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When a cell divides into two daughter cells, it must replicate its DNA according to a very specific scenario. In the presence of some disruptive elements, however, cancer cells are unable to perform this operation optimally; ...
Sep 25, 2019
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A cleft lip or palate arises from the combined effects of genes and inflammatory risk factors experienced during pregnancy, such as smoking or infections, finds a new study led by UCL researchers.
May 24, 2023
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Researchers can now identify DNA regions within non-coding DNA, the major part of the genome that is not translated into a protein, where mutations can cause diseases such as cancer.
Oct 3, 2013
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An international team of researchers has identified DNA mutations in a gene that senses viral RNA, as a cause of the autoimmune disease lupus, with the finding paving the way for the development of new treatments.
Apr 27, 2022
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347
Genetic mutations that drive the development of a common type of childhood leukaemia can be traced back to errors by the immune system during the production of antibodies.
Mar 22, 2019
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A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, ...
Jun 2, 2022
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Colorectal cancer patients with defects in mismatch repair--one of the body's systems for repairing DNA damage--have lower recurrence rates and better survival rates than patients without such defects, according to a study ...
May 19, 2011
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In 2006, scientists discovered a way to "reprogram" mature cells—adult skin cells, for example—into stem cells that could, in principle, give rise to any tissue or organ in the body. Many assumed it was only a matter ...
Aug 19, 2019
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A simple blood test can rapidly and accurately detect mutations in two key genes in non-small cell lung tumors, researchers at Dana-Farber Cancer Institute and other institutions report in a new study - demonstrating the ...
Apr 7, 2016
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