Medical research

Defective DNA damage repair leads to chaos in the genome

Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now found a cause for frequent catastrophic events in the genetic material of cancer cells that have only been known for a few ...

Oncology & Cancer

A counterintuitive approach to fighting cancer

When you're under attack, you fight back. You gather your troops and attack the invading enemy, hoping to wound and defeat them, while supporting and treating your own injured soldiers. It's common sense.

Medical research

New study unravels mystery of a DNA repair process

(Medical Xpress) -- Scientists at the University of Sussex have uncovered the mechanism of a key process in DNA repair that helps prevent neurodegenerative diseases such as ataxia.

Genetics

An enzyme that fixes broken DNA sometimes destroys it instead

Enzymes inside cells that normally repair damaged DNA sometimes wreck it instead, researchers at the Stanford University School of Medicine have found. The insight could lead to a better understanding of the causes of some ...

Medical research

Building bridges: PARP enzymes bring broken DNA together

Scientists at St. Jude Children's Research Hospital have identified the structure of double-strand DNA break repair by PARP enzymes. The findings show that PARP2 can bridge the gap, bringing two broken DNA ends together.

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