In a series of experiments using human cancer cell lines, scientists at Johns Hopkins Medicine say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel ...
Jun 17, 2020
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The three-dimensional structure of the human genome is essential for providing a rapid and robust inflammatory response, but is surprisingly not vital for reprogramming one cell type into another, according to research published ...
Jun 8, 2020
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Scientists at St. Jude Children's Research Hospital are studying the combined effect of cancer treatments and inherited mutations in DNA-repair genes. Their results may help predict which survivors are at increased risk of ...
Jun 4, 2020
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Our cells have several ways to repair DNA that breaks when the cells divide. However, genetic mutations can disable these DNA repair mechanisms, destabilize the cells, and trigger cancer. In a paper published today in the ...
Jun 4, 2020
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Patients with metastatic pancreatic cancer who had germline or somatic mutations in DNA repair genes had better clinical outcomes after platinum-based chemotherapy, as compared with patients without these mutations, according ...
May 22, 2020
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MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions. This enzyme is often diminished in both Alzheimer's ...
May 18, 2020
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Selective serotonin reuptake inhibitors, or SSRI's, are popular drugs that treat depression by increasing the amount of a neurotransmitter called serotonin in the brain. But when a common SSRI known as sertraline is taken ...
May 15, 2020
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A drug already licensed for the treatment of breast and ovarian cancers is more effective than targeted hormone therapy at keeping cancer in check in some men with advanced prostate cancer, a major clinical trial reports.
Apr 28, 2020
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A global collaboration of scientists has more than doubled the known number of regions on the human genome that influence the risk of developing melanoma.
Apr 27, 2020
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Launching a two-pronged attack on cancer's ability to safeguard its DNA could offer an effective new way of treating the disease, a new study reports.
Mar 12, 2020
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