Instead of relying on the cell's repair mechanisms, the vaccinia virus MacGyvers a tool for DNA repair from one that it already uses to copy DNA, reports a team of researchers at the Medical University of South Carolina (MUSC) ...
May 17, 2022
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A totipotent cell is a single cell that can give rise to a new organism, if given appropriate maternal support. Totipotent cells have many properties, but we do not know all of them yet. Researchers at Helmholtz Munich have ...
Mar 7, 2022
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Huntington's disease (HD) is a dominantly inherited neurodegenerative disease characterized by expansion of the number of trinucleotide CAG repeats in the first exon of the HTT gene encoding the protein huntingtin. While ...
There are many types of cancer treatments. But which ones work best varies from patient to patient. Currently, doctors determine which treatment to try for a patient based on where in their DNA, or genetic code, the error ...
Oct 26, 2021
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New research exploring theories of aging has found that small mutations accumulating in DNA are unlikely to be fully responsible for this process.
Oct 1, 2021
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The mutations that give rise to melanoma result from a chemical conversion in DNA fueled by sunlight—not just a DNA copying error as previously believed, reports a study by Van Andel Institute scientists published today ...
Jul 30, 2021
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After the p53 tumor suppressor gene, the genes most frequently found mutated in cancer are those encoding two proteins of the SWI/SNF chromatin remodeling complex. This complex's function is to 'accommodate' the histones ...
May 14, 2021
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Meier-Gorlin syndrome, or MGS, is a rare genetic developmental disorder that causes dwarfism, small ears, a small brain, missing patella and other skeletal abnormalities. In severe cases, MGS results in miscarriages and stillbirths.
Dec 15, 2020
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Sydney researchers have found cancer cells can repair their DNA by using 'cables' in their nucelus. The findings open new possibilities for designing future cancer treatments.
Dec 1, 2020
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Researchers at the Karolinska Institutet have discovered a new interaction between two proteins that reduce the risk of DNA damage and cellular cancer development. The findings on the proteins RTEL1 and Poldip3 are published ...
Jun 18, 2020
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