The protein TCF-1 enables various parts of otherwise insulated DNA segments to intermingle in a way that is required for the development of T cells—a key element of the body's immune system—and the role this protein plays ...
Jun 20, 2022
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The chemical bisphenol F (found in plastics) can induce changes in a gene that is vital for neurological development. This discovery was made by researchers at the universities of Uppsala and Karlstad, Sweden. The mechanism ...
May 20, 2021
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Cancer cells are known for spreading genetic chaos. As cancer cells divide, DNA segments and even whole chromosomes can be duplicated, mutated, or lost altogether. This is called chromosomal instability, and scientists at ...
Dec 28, 2020
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Myotonic dystrophy type I is the most common type of adult-onset muscular dystrophy. People with the condition inherit repeated DNA segments that lead to the toxic buildup of repetitive RNA, the messenger that carries a gene's ...
Sep 14, 2020
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Huntington's disease (HD), an inherited and fatal disorder in which nerve cells in the brain break down over time, may become evident at any time in life but typically starts in a person's 30s or 40s. New research results ...
Aug 8, 2019
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Chromosomes perform an intricate dance inside the nuclei of cells undergoing meiosis (dividing into sperm and eggs). One stumble can lead to infertility, miscarriage, birth defects or tumor formation.
Dec 1, 2016
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A study led by Dr K.C. Tan-Un and her team at the School of Biological Sciences, the University of Hong Kong (HKU), in collaboration with Professor Richard Festenstein at the Clinical Sciences Centre, Imperial College London, ...
Nov 2, 2016
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St. Jude Children's Research Hospital scientists have developed a significantly better computer tool for finding genetic alterations that play an important role in many cancers but were difficult to identify with whole-genome ...
May 4, 2015
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The geneticist Sébastien Jacquemont is the new holder of the Canada Research Chair in Genetics of Neurodevelopmental Disorders and Associated Dysregulation in Energy Balance at the University of Montreal. He moved to the ...
Feb 25, 2015
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Researchers in human genetics have known that long nucleotide repeats in DNA lead to instability of the genome and ultimately to human hereditary diseases such Freidreich's ataxia and Huntington's disease.
Nov 25, 2014
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