Alcohol exposure in early pregnancy can change gene function during the tightly regulated embryonic development, and consequently cause developmental disorders—especially neurodevelopmental disorders. Novel information ...
Jan 3, 2023
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A research team led by Hong Kong Baptist University (HKBU) has identified a molecular target for bone anabolic therapies using a selected aptamer that serves as an inhibitor of sclerostin, a protein that prevents bone growth. ...
Dec 19, 2022
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BRCA1 (BReast CAncer Gene 1), a key gene that becomes faulty in some instances, leading to breast and ovarian cancer, plays an important role in the body's DNA repair mechanisms. BRCA1, once mutated, can cause cancer to develop. ...
Nov 17, 2022
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A team of researchers at the University of Pennsylvania, working with a colleague from the University of Texas Medical Branch and another from Boston University and Boston Medical Center, has found that the SARS-CoV-2 virus ...
Researchers have uncovered a novel pathway that explains how cancer cells become resistant to chemotherapies, which in turn offers a potential solution for preventing chemo-resistance.
Sep 20, 2022
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Scientists have found that non-coding "junk" DNA, far from being harmless and inert, could potentially contribute to the development of cancer.
Jul 19, 2022
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An international team of researchers has found that some tumor cells are able to set off a caspase-activated DNAse (CAD) that promotes breaks in DNA strands after exposure to genotoxic treatments. In their paper published ...
While cancer therapies targeting specific genes or disease pathways can extend lives, they can also lead to highly resistant tumors when small reservoirs of cancer cells survive treatment, grow, and spread.
Mar 30, 2022
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Killing cancer cells without affecting surrounding normal cells is the most desirable approach for targeted cancer therapy. However, it cannot be easily achieved due to the similarities in the properties between normal and ...
Feb 22, 2022
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Two new studies of the developing human brain are helping researchers reconcile a long-held debate over how the brain forms. The research appears Oct. 6 in a special issue of Nature highlighting studies that contribute to ...
Oct 7, 2021
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