Researchers identify new potential target for cancer therapy
Researchers at UT Southwestern Medical Center have found that alternative splicing – a process that allows a single gene to code for multiple proteins – appears to be a new potential target for anti-telomerase ...
Cancer
Apr 19, 2013 |
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You don't 'own' your own genes: Researchers raise alarm about loss of individual 'genomic liberty' due to gene patents
Humans don't "own" their own genes, the cellular chemicals that define who they are and what diseases they might be at risk for. Through more than 40,000 patents on DNA molecules, companies have essentially ...
Genetics
Mar 26, 2013 |
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Molecule's structure reveals new therapeutic opportunities for rare diabetes
Researchers at Sanford-Burnham Medical Research Institute have determined the complete three-dimensional structure of a protein called HNF-4α. HNF-4α controls gene expression in the liver and pancreas, ...
Medical research
Mar 13, 2013 |
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Life experiences put their stamp on the next generation: New insights from epigenetics
The 18th century natural philosopher Jean-Baptiste Lamarck proposed that the necks of giraffes lengthened as a consequence of the cumulative effort, across generations, to reach leaves just out of their grasp. This view of ...
Psychology & Psychiatry
Feb 14, 2013 |
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Scientists create one-step gene test for mitochondrial diseases
More powerful gene-sequencing tools have increasingly been uncovering disease secrets in DNA within the cell nucleus. Now a research team is expanding those rapid next-generation sequencing tests to analyze a separate source ...
Medical research
Jan 29, 2013 |
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Novel technique reveals dynamics of telomere DNA structure
Biomedical researchers studying aging and cancer are intensely interested in telomeres, the protective caps on the ends of chromosomes. In a new study, scientists at UC Santa Cruz used a novel technique to reveal structural ...
Medical research
Jan 17, 2013 |
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Researchers find new culprit in castration-resistant prostate cancer
Scientists at Dana-Farber Cancer Institute have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, which normally are needed to spur the cancer's growth. They ...
Cancer
Dec 13, 2012 |
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Scientists identify liposarcoma tumors that respond to chemotherapy
Liposarcoma, the most common type of sarcoma, is an often lethal form of cancer that develops in fat cells. It is particularly deadly, in part, because the tumors are not consistently visible with positron emission tomography ...
Cancer
Dec 10, 2012 |
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Abnormal DNA maintenance related to cancer
DNA, like houses and cars, needs ongoing maintenance. Rays of ultraviolet sunlight, chemical pollutants and normal biochemical processes in the cell can damage it. Cells routinely repair this damage before making proteins ...
Cancer
Dec 10, 2012 |
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New findings on men's genes could alter interpretation of PSA test
By studying a specific part of the male DNA, it may be possible to refine the interpretation of PSA tests. This would reduce the risk of men being treated for prostate cancer unnecessarily.
Cancer
Oct 30, 2012 |
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Obese moms give birth to heart healthier kids following bariatric surgery
Kids born to moms who have lost a substantial amount of weight after undergoing bariatric surgery have fewer cardiovascular risk factors than their siblings who were born before the weight loss surgery.
Surgery
Oct 29, 2012 |
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UNM Cancer Center researcher looks for genetic markers for ovarian cancer
Ovarian cancer is a deadly disease. With no overt symptoms and no screening tests to catch it early, ovarian cancer is often detected at stage 3 or later. By then, it can be very aggressive and may have spread beyond the ...
Cancer
Oct 23, 2012 |
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Uncovering the genome's regulatory code
Since the sequencing of the human genome in 2001, all our genes – around 20,000 in total – have been identified. But much is still unknown – for instance where and when each is active. Next to each ...
Genetics
Sep 10, 2012 |
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TB outbreaks could be 'solved' by DNA tracking
Reconstructing the spread of killer diseases such as tuberculosis (TB) from person to person using DNA sequencing quickly identifies the origin and movement of pathogens. This approach is directly informing ...
Diseases, Conditions, Syndromes
Sep 03, 2012 |
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Sending out an SOS: How telomeres incriminate cells that can't divide
The well-being of living cells requires specialized squads of proteins that maintain order. Degraders chew up worn-out proteins, recyclers wrap up damaged organelles, and-most importantly-DNA repair crews ...
Medical research
Mar 12, 2012 |
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