Chromatin marks the spot in search for disease pathways
In September 2012, the Encyclopedia of DNA Elements (ENCODE) Project Consortium, a multi-institution collaboration that included the Broad Institute, capped off nine years of research with a flurry of papers ...
Genetics
Jan 07, 2013 |
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Study suggests human genes influence gut microbial composition
New research led by the Karolinska Institutet, Sweden and the University of Glasgow, Scotland, has identified a link between a human gene and the composition of human gastrointestinal bacteria. In a study published as a letter ...
Medical research
Jan 07, 2013 |
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Breast milk contains more than 700 bacteria: Microbes taken from breast milk by the infant are identified
Spanish researchers have traced the bacterial microbiota map in breast milk, which is the main source of nourishment for newborns. The study has revealed a larger microbial diversity than originally thought: ...
Health
Jan 04, 2013 |
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Researchers uncover novel role of BRCA1 in regulating the survival of skin stem cells
Our DNA, which stores our genetic information, is constantly exposed to damage. If not properly repaired, DNA damage can lead to cell death. This, in turn, can lead to tissue exhaustion and ageing, or induce mutations resulting ...
Cancer
Jan 03, 2013 |
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Researchers find peptide produced by giant panda fights fungi and bacteria
(Medical Xpress)—Researchers working at the Life Sciences College of Nanjing Agricultural University in China have found that giant pandas naturally produce a peptide that can kill fungi and bacteria. In ...
Medical research
Jan 03, 2013 |
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New findings in the search for genetic clues to insulin production
In research published online Dec. 23, 2012 in the journal Nature Genetics, scientists have found three new and relatively rare genetic variants that influence insulin production, offering new clues about ...
Genetics
Dec 23, 2012 |
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Targeted gene silencing drugs are more than 500 times more effective with new delivery method
Small interfering RNAs (siRNAs) are a potent new drug class that can silence a disease-causing gene, but delivering them to a target cell can be challenging. An innovative delivery approach that dramatically ...
Medical research
Dec 21, 2012 |
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Search for epigenetic decoder leads scientists to Rett Syndrome
(Medical Xpress)—A few years ago, scientists discovered an unexpected layer of information woven into the genetic code – a nucleotide called 5-hydroxymethylcytosine, or 5hmC. Its meaning was unknown at the time, but a ...
Medical research
Dec 21, 2012 |
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Genomic 'hotspots' offer clues to causes of autism, other disorders
An international team, led by researchers from the University of California, San Diego School of Medicine, has discovered that "random" mutations in the genome are not quite so random after all. Their study, ...
Genetics
Dec 20, 2012 |
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Toasting your health: Take care with alcohol consumption
(Medical Xpress)—The holidays are a time to consume—food, gifts, and spirits. Here are a few alcohol-related story ideas from The Methodist Hospital. Because alcohol's effects on human physiology are complex, advice about ...
Health
Dec 20, 2012 |
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New study shows how mitochondrial disease may be prevented
A joint team of scientists from The New York Stem Cell Foundation (NYSCF) Laboratory and Columbia University Medical Center (CUMC) has developed a technique that may prevent the inheritance of mitochondrial diseases in children. ...
Medical research
Dec 19, 2012 |
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Cancer study overturns current thinking about gene activation
(Medical Xpress)—A new Australian study led by Professor Susan Clark from Sydney's Garvan Institute of Medical Research shows that large regions of the genome – amounting to roughly 2% – are epigenetically activated ...
Cancer
Dec 18, 2012 |
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Study shows starving cancer cells of key nutrient slows tumour growth
Depriving cancer cells of a key amino acid dramatically cuts their ability to grow and multiply, according to a new Cancer Research UK study published in Nature.
Cancer
Dec 18, 2012 |
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Changes in progenitor cell population in breast may be overlooked factor in breast cancer
The DNA mutations that accumulate over time as women age are not the sole contributor to the higher frequency of breast cancer in women over 50, Mark LaBarge, PhD, a researcher at Lawrence Berkeley National Laboratory (LBNL) ...
Cancer
Dec 17, 2012 |
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Scientists discover gene linked to breast and ovarian cancer
(Medical Xpress)—A team of researchers led by the Institute of Cancer Research, London, have found that rare mutations in a gene called PPM1D are linked to an increased risk of breast and ovarian cancer. The mutations are ...
Cancer
Dec 17, 2012 |
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