Science of genome-sequencing marks 10 years
A decade after completion of the Human Genome Project on April 14, 2003, a top official of the National Institutes of Health surveyed the rarefied view from that mountaintop:
Genetics
Apr 15, 2013 |
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Genetic variation contributes to pulmonary fibrosis risk
A newly published study of patients with pulmonary fibrosis has discovered multiple genetic variations that should help with future efforts to treat the disease.
Genetics
Apr 15, 2013 |
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Resistance is futile: Researchers identify gene that mediates cisplatin resistance in ovarian cancer
Platinum compounds, such as cisplatin and carboplatin, induce DNA cross-linking, prohibiting DNA synthesis and repair in rapidly dividing cells. They are first line therapeutics in the treatment of many solid tumors, but ...
Cancer
Apr 15, 2013 |
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Genetic discovery found to influence obesity in people of African ancestry
The largest genetic search for "obesity genes" in people of African ancestry has led to the discovery of three new regions of the human genome that influence obesity in these populations and others.
Genetics
Apr 15, 2013 |
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Court: Can human genes be patented? (Update)
The Supreme Court grapples Monday with the question of whether human genes can be patented, and the ultimate answer could reshape U.S. medical research, the fight against diseases like breast and ovarian ...
Genetics
Apr 15, 2013 |
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Ten years on, still much to be learned from human genome map
(HealthDay)—As scientists mark the 10th anniversary Sunday of the completion of the Human Genome Project, they will note how that watershed effort has led to the discovery of the genetic underpinnings of ...
Genetics
Apr 12, 2013 |
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Deciphering the cellular reading system of DNA methylation
(Medical Xpress)—Scientists from the FMI identify how a family of proteins reads the methylation marks on the DNA so critical for cell development. These MBD proteins bind directly to methylation marks ...
Genetics
Apr 12, 2013 |
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Are human genes patentable?
(Medical Xpress)—On April 15, the Supreme Court will hear oral argument in Association for Molecular Pathology v. Myriad Genetics, a case that could answer the question, "Under what conditions, if any, ...
Genetics
Apr 11, 2013 |
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How Alzheimer's could occur: Protein spheres in the nucleus give wrong signal for cell division
A new hypothesis has been developed by researchers in Bochum on how Alzheimer's disease could occur. They analysed the interaction of the proteins FE65 and BLM that regulate cell division. In the cell culture ...
Alzheimer's disease & dementia
Apr 11, 2013 |
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Weight loss surgery not only shrinks waists but also affects genes
Gastric bypass surgery can drastically reduce the body weight of obese individuals in a short timeframe. For reasons that are not entirely clear, the surgery also leads to early remission of type 2 diabetes in the vast majority ...
Medical research
Apr 11, 2013 |
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Vet drug bute found in British corned beef
British supermarket chain Asda on Tuesday recalled all of its budget corned beef range after veterinary drug phenylbutazone was found in some samples.
Health
Apr 09, 2013 |
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Excess estrogen in pregnancy can silence BRCA1 in daughters, increasing breast cancer risk
Excess estrogen levels during pregnancy can disable, in their daughters, a powerful breast cancer tumor suppressor gene, say researchers at Georgetown Lombardi Comprehensive Cancer Center. They found the DNA repair gene BRCA1 ...
Cancer
Apr 09, 2013 |
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Newly discovered blood protein solves 60-year-old riddle
Researchers at Lund University in Sweden have discovered a new protein that controls the presence of the Vel blood group antigen on our red blood cells. The discovery makes it possible to use simple DNA testing ...
Genetics
Apr 08, 2013 |
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Protecting against aging at the molecular level
Research from Western University and Lawson Health Research Institute sheds new light on a gene called ATRX and its function in the brain and pituitary. Children born with ATRX syndrome have cognitive defects and developmental ...
Medical research
Apr 08, 2013 |
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Researchers identify transcription factors that regulate retinal vascularization
The retina is a highly vascularized tissue, but too much or too little vascularization can lead to visual impairment and diseases such as familial exudative vitreoretinopathy or macular degeneration. In this issue of the ...
Medical research
Apr 08, 2013 |
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