Addiction

Blocking dopamine weakens effects of cocaine

Blocking dopamine receptors in different regions of the amygdala reduces drug seeking and taking behavior with varying longevity, according to research in rats published in eNeuro.

Neuroscience

Unraveling the brain's reward circuits

To some, a chocolate cake may spark a shot of pleasure typically associated with illicit drugs. A new study by Penn biologists offers some insights into that link, revealing new information about how the brain responds to ...

Neuroscience

Breaking the stress and drug abuse connection

When people undergo stress, some turn to alcohol or other drugs to help them cope. Most of us, certainly, have had the experience of cracking open a beer to relax at the end of a tough day. But in cases of extreme or long-term ...

Neuroscience

Brain research reveals a circuit for cocaine relapse

Approximately 1.5 million Americans use cocaine in a given year, according to the National Institute on Drug Abuse. Many are repeat users. Unfortunately, there are currently no FDA-approved medicinal treatments for cocaine ...

Neuroscience

Nature versus nurture and addiction

The progressive understanding of addiction as a disease rather than a choice has opened the door to better treatment and research, but there are aspects of addiction that make it uniquely difficult to treat.

Neuroscience

Moving the motivation meter

Two novel drugs kickstart motivation in rats suffering from apathy and a lack of oomph, UConn researchers reported at the Society for Neuroscience conference in San Diego on Nov. 5.

Neuroscience

Dopamine drives early addiction to heroin

Scientists have made a major advance in untangling the brain circuits that lead to the powerful addictive effects of heroin, a study in the open-access journal eLife reports.

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