News tagged with double helix
Related topics: dna
In geometry a double helix (plural helices) typically consists of two congruent helices with the same axis, differing by a translation along the axis, which may or may not be half-way.
The term "double helix" is commonly encountered in molecular biology, where it refers to the structure of DNA. The double-helix model of DNA structure was first published in the journal Nature by James D. Watson and Francis Crick in 1953, based upon the crucial X-ray diffraction image of DNA (labeled as "Photo 51") from Rosalind Franklin in 1952 , followed by her more clarified DNA image with Raymond Gosling, Maurice Wilkins, Alexander Stokes and Herbert Wilson, as well as base-pairing chemical and biochemical information by Erwin Chargaff.
Crick, Wilkins and Watson each received one third of the 1962 Nobel Prize in Physiology or Medicine for their contributions to the discovery. (Franklin, whose breakthrough X-ray diffraction data was used to formulate the DNA structure, died in 1958, and thus was ineligible to be nominated for a Nobel Prize.)
The DNA double helix is a right-handed spiral polymer of nucleic acids, held together by nucleotides which base pair together. A single turn of the helix constitutes ten nucleotides. The double helix structure of DNA contains a major groove and minor groove, the major groove being wider than the minor groove. Given the difference in widths of the major groove and minor groove, many proteins which bind to DNA do so through the wider major groove .
The order, or sequence, of the nucleotides in the double helix within a gene specifies the primary structure of a protein.
The term entered popular culture with the publication in 1968 of The Double Helix: A Personal Account of the Discovery of the Structure of DNA, by James Watson.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
Our genetic material is constantly exposed to damage, which the body's own proteins normally repair. One of these proteins works like a scanner, continually scouring the genetic material for signs of damage. ...
Genetics Jan 24, 2013 | 4 / 5 (2) | 0 |
In a new paper he regards "among my most important work since the double helix," Nobelist James Watson sets forth a novel hypothesis regarding the role of oxidants and antioxidants in cancers that are currently incurable, ...
Cancer Jan 08, 2013 | 5 / 5 (4) | 0 |
A person doesn't have to go far to find a polycyclic aromatic hydrocarbon (PAH). These carcinogen precursors are inhaled through automobiles exhaust during the morning commute, are present in a drag of cigarette ...
Cancer Nov 02, 2012 | not rated yet | 0 |
Researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab), through a combination of time-lapse live imaging and mathematical modeling of a special line of ...
Cancer Dec 20, 2011 | 4.5 / 5 (11) | 4 |
When RNA component units called ribonucleotides become embedded in genomic DNA, which contains the complete genetic data for an organism, they can cause problems for cells. It is known that ribonucleotides ...
Cancer Dec 04, 2011 | 5 / 5 (2) | 0 |
Scientists from the universities of Zurich and Duisburg-Essen have discovered a specific function of the protein p97/VCP. They demonstrate that the protein repairs DNA breaks like a corkscrew, a repair mechanism that could ...
Medical research Nov 08, 2011 | 5 / 5 (3) | 0
As our bodies first form, developing cells are a lot like children put on the school bus with their names and addresses pinned to their shirts.
Medical research Jul 01, 2011 | not rated yet | 0 |