A drug candidate discovered and developed decades ago in the laboratory of UC Davis distinguished professor Bruce Hammock may help control the body's raging and often deadly inflammatory response to chemotherapy treatments, ...
Sep 28, 2021
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48
Researchers have created a new open-access database of information on drug candidates and how they are metabolized by the body, which could help speed up the repurposing of old drugs as new treatments.
Aug 3, 2021
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200
It usually takes 10 to 15 years to develop a new drug, and they cost around US$2.6 billion each. Because it's difficult to predict how a drug candidate will interact with human cells, many drugs never pass clinical trials. ...
Jul 27, 2021
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18
A new University of Chicago study has found that the drug masitinib may be effective in treating COVID-19.
Jul 21, 2021
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236
Mining the world's most comprehensive drug repurposing collection for COVID-19 therapies, scientists have identified 90 existing drugs or drug candidates with antiviral activity against the coronavirus that's driving the ...
Jun 3, 2021
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29
Researchers at The University of Texas MD Anderson Cancer Center have discovered a novel function for the metabolic enzyme medium-chain acyl-CoA dehydrogenase (MCAD) in glioblastoma (GBM). MCAD prevents toxic lipid buildup, ...
May 26, 2021
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7
Scientists have shown that two existing drug candidates—JAK inhibitors and Mepron—hold potential as treatments for a deadly acute myeloid leukemia (AML) subtype that is more common in children.
Apr 14, 2021
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51
Patients who have surgery for esophageal cancer commonly see the disease return, but a drug that boosts the immune system may help delay or prevent that, a new trial has found.
Apr 1, 2021
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12
Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a drug candidate that blocks the uptake of glutamine, a key food source for many tumors, and slows the growth of melanoma. The drug is a small ...
Mar 19, 2021
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113
Scientists at Sanford Burnham Prebys Medical Discovery Institute demonstrated for the first time that blocking 'cell drinking,' or macropinocytosis, in the thick tissue surrounding a pancreatic tumor slowed tumor growth—providing ...
Mar 17, 2021
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