News tagged with drug candidates
Awakening to new drugs against sleeping sickness
Sleeping sickness kills tens of thousands of people in Africa each year. Current chemotherapies are subject to various limitations, including resistance. Rhodesain, an enzyme of the parasites that cause this ...
Cancer
May 17, 2013 |
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Firefly protein lights up degenerating muscles, aiding muscular-dystrophy research
Stanford University School of Medicine scientists have created a mouse model of muscular dystrophy in which degenerating muscle tissue gives off visible light. The observed luminescence occurs only in damaged muscle tissue ...
Medical research
Apr 24, 2013 |
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Researchers develop implantable, bioengineered rat kidney (w/ video)
Bioengineered rat kidneys developed by Massachusetts General Hospital (MGH) investigators successfully produced urine both in a laboratory apparatus and after being transplanted into living animals. In their ...
Medical research
Apr 14, 2013 |
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Clinical trial results for BIND-014 presented at AACR 2013
The nanoparticle drug BIND-014 is effective against multiple solid tumors, according to results generated by the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare, and presented today at the American ...
Cancer
Apr 09, 2013 |
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Rigosertib Phase 1 results lead to disease-focused Phase 2 development
Results of a phase 1 clinical trial reported at the American Association for Cancer Research (AACR) annual conference show that orally administered Rigosertib is well tolerated in patients with advanced solid tumors. This ...
Cancer
Apr 09, 2013 |
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Researchers help find new therapeutic target for treating traumatic brain injury
(Medical Xpress)—A research team including members of the Department of Bioengineering in the University of Pennsylvania School of Engineering and Applied Science has discovered that drug intervention to reduce intercellular ...
Neuroscience
Apr 09, 2013 |
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Malaria vaccine fails to work after four years
A new vaccine that has raised hopes of becoming a potent new tool in the battle against malaria seems to stop working in children after four years, according to research published Wednesday.
Medications
Mar 20, 2013 |
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Tapeworm DNA contains drug weak spots
For the first time, researchers have mapped the genomes of tapeworms to reveal potential drug targets on which existing drugs could act. The genomes provide a new resource that offers faster ways to develop urgently needed ...
Diseases, Conditions, Syndromes
Mar 13, 2013 |
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Study links US mortality rates under age 50 to life expectancy lagging other high-income countries
(Medical Xpress)—Higher mortality rates among Americans younger than 50 are responsible for much of why life expectancy is lower in the United States than most of the world's most developed nations.
Health
Mar 12, 2013 |
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Mining for new drugs in the ocean
Each time we use an antibiotic, the weaker strains of infection are killed off while the stronger, more virulent strains are left behind to multiply. In the past, this has not caused much concern, as there ...
Medications
Feb 28, 2013 |
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New flu drug stops virus in its tracks
A new class of influenza drug has been shown effective against drug-resistant strains of the flu virus, according to a study led by University of British Columbia researchers.
Medical research
Feb 21, 2013 |
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New hope in fight against multi-resistant germs
An increasing number of bacteria is evolving antibiotic resistance. Much-feared representatives of this steadily growing group include Staphylococci strains. At this point, multi-resistant forms of the ba ...
Diseases, Conditions, Syndromes
Feb 13, 2013 |
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In the brain, broken down 'motors' cause anxiety
When motors break down, getting where you want to go becomes a struggle. Problems arise in much the same way for critical brain receptors when the molecular motors they depend on fail to operate. Now, researchers reporting ...
Medical research
Feb 07, 2013 |
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NIH clinical trial begins for treatment of rare, fatal neurological disorder
A clinical trial to evaluate a drug candidate called cyclodextrin as a possible treatment for Niemann-Pick disease type C1 (NPC), a rare and fatal genetic disease, will start today, researchers announced. Scientists from ...
Diseases, Conditions, Syndromes
Jan 23, 2013 |
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Doubling down against diabetes: Turbo-charged gut hormones
A collaboration between scientists in Munich, Germany and Bloomington, USA may have overcome one of the major challenges drug makers have struggled with for years: Delivering powerful nuclear hormones to specific tissues, ...
Medical research
Nov 13, 2012 |
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