Oncology & Cancer

Scientists alter 3-D genome using 'small molecules'

Researchers have discovered that the spatial organization of the genome can be altered using small molecule compounds which are considered as promising anti-cancer drugs. This work opens up the prospect of developing a new ...

Oncology & Cancer

Balance of two enzymes linked to pancreatic cancer survival

Protein Kinase C (PKC) enzymes are crucial for a number of cellular activities, including cell survival, proliferation and migration—functions that must be carefully controlled lest cells get out of control and form a tumor. ...

Genetics

A quick path to antimalarial resistance

Resistance to antimalarial drugs is thought to result mainly from changes in the parasite's genome. However, P. falciparum can also develop resistance to some antimalarial compounds by epigenetic changes, according to a new ...

Diseases, Conditions, Syndromes

Drug design strategy boosts the odds against resistance development

A new rational drug design technique that uses a powerful computer algorithm to identify molecules that target different receptor sites on key cellular proteins could provide a new weapon in the battle against antibiotic ...

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